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Optimal strategies for monitoring lipid levels in patients at risk or with cardiovascular disease: systematic review with statistical and cost-effectiveness modelling

Lipid measurement is essential for calculating an individual’s overall risk of cardiovascular disease and coronary heart disease. We already know that using statins reduces coronary heart disease mortality among those at both moderate and high risk of CHD. 

The overall aim of the project will be to identify the optimal strategies for monitoring lipid levels, including a cost-effectiveness model. Are key objectives are:

  • To identify the relative ability of different lipid measures (single or combination) for detecting important changes in lipid status,
  • To estimate the incremental gain and costs of different strategies (lipid measurements and intervals) for risk assessment and monitoring of lipid levels in patients at risk of or with cardiovascular disease,
  • To develop and populate an economic model of lipid monitoring,
  • To explore how the choice of lipid measure impacts on risk assessment of CVD compared with original risk scores,
  • To disseminate the impact of our findings on CVD risk assessment


Video from the Monitoring Dissemination Meeting

The role of early dissemination meetings in the research process


Final report accepted 19th December 2015.  Publication expected June 2015.

For further information please conatct Emily McFadden.

This project was funded by the National Institute for Health Research Health Technology Assessment (NIHR HTA) Programme (project number 10/97/01) and will be published in full in Health Technology Assessment

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