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I have supervised DPhil and MSC graduates for the last 10 years. At the moment I supervise 3 DPhil projects looking at determining the strength of evidence in Systematic Reviews, best ways for monitoring patients with Chronic Heart Failure, and how to improve the uptake of Clinical Prediction rules in Clinical Practice.
My primary research program focuses on monitoring in primary care, meta-analysis methods, methodology for studying infectious diseases in children, and assessing complex interventions.
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DPhil MSc MA
Director Medical Statistics
- Professor of Medical Statistics
My main activity is as Director of the Statistics group in the Nuffield Department of Primary Care Health Sciences (NDPCHS) which I joined in 2002. I am involved in a number of research activities within the department; however my main focus is the study of Monitoring for the management of long-term conditions (e.g. Type 2 diabetes, hypertension, etc).
I have overseen the development of one of the strongest methodological/statistical groups in the UK (across all clinical areas) with a particular emphasis on Monitoring, with my group achieving national and international recognition [NIHR Progress Report 2008/09-Delivering Health Research]. As part of this, I am the Statistical director of our fully accredited Clinical Trials Unit (only 55 units have received full accreditation in the UK).
I sit on a range of national and international panels and boards that influence healthcare policy at different levels (funding boards, steering groups, data monitoring boards, etc.). I am also a Statistical Editor of the BMJ (since 2011) and was a member of the NIHR Health Technology Assessment (HTA) Commissioning board until 2012, joining in 2007 as Associate Member becoming a full Board Member in 2009.
I am also Director of Research Methodologies in the Centre for Evidence Based Medicine (CEBM) as well a fellow at St Hugh’s college Oxford.
Effect of 3 to 5 years of scheduled CEA and CT follow-up to detect recurrence of colorectal cancer: the FACS randomized clinical trial.
Primrose JN. et al, (2014), Jama, 311, 263 - 270
School-based programmes for preventing smoking.
Thomas RE. et al, (2013), Cochrane Database Syst Rev, 4
Self-monitoring of oral anticoagulation: Systematic review and meta-analysis of individual patient data
Heneghan C. et al, (2012), The Lancet, 379, 322 - 334
Statistical models for the control phase of clinical monitoring.
Stevens RJ. et al, (2010), Stat Methods Med Res, 19, 394 - 414
Graphical method for depicting randomised trials of complex interventions.
Perera R. et al, (2007), Bmj, 334, 127 - 129
Implications of lower risk thresholds for statin treatment in primary prevention: Analysis of CPRD and simulation modelling of annual cholesterol monitoring.
McFadden E. et al, (2014), Prev Med, 70C, 14 - 16
Response to Letter to the Editor entitled: Macroscopically detected female genital injury after consensual and non-consensual vaginal penetration: A prospective comparison study [20(2013) 884-901].
Lincoln C. et al, (2014), J Forensic Leg Med, 28, 50 - 53
Home Blood Pressure Monitoring - what is the optimal schedule? A systematic review
Hodgkinson J. et al, (2014), Journal of Human Hypertension, 28, 633 - 634
Factors associated with time to diagnosis and stage at diagnosis of lung cancer: a prospective cohort study
Walter FM. et al, (2014), European Journal of Cancer Care, 23, 3 - 3
Factors associated time to diagnosis and stage at diagnosis of colorectal cancer: a prospective cohort study
Walter FM. et al, (2014), European Journal of Cancer Care, 23, 6 - 6
NIHR Programme grant for applied research: Monitoring Long Term Conditions in Primary Care: 01/01/2014 - 31.12.2018
NIHR HTA: Optimal strategies for monitoring lipid levels in patients at risk or with cardiovascular diseases: best marker for monitoring and cost-effectiveness of different monitoring frequencies: 01/01/12 - 30/04/2014
NIHR Programme grant for applied research. The early use of Antibiotics for at Risk Children with Influenza in Primary care (the ARCHIE programme); 01/11/2013 - 31/10/2018
NIHR HTA. Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) Trial; 01/09/2013 - 31/03/2019
NIHR Programme grant for applied research. Optimising the diagnosis and management of hypertension in primary care through self monitoring of blood pressure. 01/02/2012 - 31/01/2017
NIHR. Improving Early Recognition of serious illness in children in primary care (CDF). 01/11/11 - 31/10/2016
NIHR HTA. An open randomised study of autoinflation in school age children (4-11 years) with otitis media with effusion (OME) in primary care: 01/09/11 - 31/08/2014
NIHR Programme grant for applied research. Examining the role of online patient experience.01/02/2010 - 31/01/2015
Department of Health. Cochrane Tobacco Addiction review group costs. 01/04/2010 - 31/03/2015