BSc, MSc, DPhil
Research Fellow in Medical Statistics
I am a NSPCR Research Fellow in Medical Statistics with a particular interest in improving the clinical utility of diagnostic research.
I lead the methodological workstream of the National Institute for Health Research Diagnostic Evidence Cooperative Oxford which aims to improve the ‘bench to bedside’ pathway for new diagnostics in primary care. In particular, I am looking at whether we can use existing evidence relating to diagnostic tests collected in the secondary care setting to inform primary care practice.
I am also the lead statistician on a programme of research exploring alternative strategies for monitoring patients who have undergone curative surgery for colorectal cancer. We are currently carrying out a Cochrane Systematic Review to evaluate the diagnostic accuracy of Carcinoembryonic antigen (CEA) for colorectal cancer recurrence. Alongside this, we are exploring how best interpret serial CEA measurements to facilitate early detection.
I co-ordinate the statistics teaching on the MSc and DPhil in Evidence-Based Heath Care. I teach on a number of the Masters modules, including but not limited to topics such as research methods, how to teach EBM, and methods relating to diagnosis and screening. I also teach statistics to undergraduate and graduate entry medical students.
My DPhil project evaluated and expanded on methodologies relating to the reporting and analysis of intermediate test results in diagnostic research.
Prior to joining the department in 2010, I completed a BSc (Hons) in Psychology at the University of Kent and an MSc in Applied Statistics at the University of St. Andrews.
Carcinoembryonic Antigen Monitoring to Detect Recurrence of Colorectal Cancer: How Should We Interpret the Test Results?
Shinkins B. et al, (2014), Clinical Chemistry (Washington, Dc): International Journal of Molecular Diagnostics and Laboratory Medicine
Blood CEA levels for detecting recurrent colorectal cancer (Protocol)
Nicholson BD. et al, (2014), Cochrane Database of Systematic Reviews
Pre-hospital risk factors for inpatient death from severe febrile illness in malian children.
Willcox ML. et al, (2014), Plos One, 9
Diagnostic uncertainty: dichotomies are not the answer.
Shinkins B. and Perera R., (2013), Br J Gen Pract, 63, 122 - 123
Diagnostic accuracy studies: how to report and analyse inconclusive test results.
Shinkins B. et al, (2013), Bmj, 346