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We looked at our HIV + Slow Progressors Cohort to determine if there were any HLA correlates for protection. No statistically significant allelic differences were found between the HIV + and control cohorts using regression analysis, though trends were noted. Data for Elite Controllers showed increased frequency of B*57. Likewise, no correlation was inferred with the clinical data of the HIV + cohort. We hypothesize that the protective effect of HLA alleles may have been lost over time.

Original publication

DOI

10.1097/QAD.0000000000000011

Type

Journal article

Journal

AIDS

Publication Date

12/08/2013