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More than one thousand people receive a cancer diagnosis in the UK each day, making early detection and intervention critical for improving outcomes for patients. The majority of patients are first diagnosed after presenting cancer symptoms to their GP. This puts primary care in a unique and critical position to drive forward research that closes the cancer care gap – the theme of this year’s World Cancer Day.
UK cancer registry data is as accurate and timely as on-site trial data, new study shows
Cancer
11 October 2024
Researchers from the Cancer Theme at Nuffield Department of Primary Care Health Sciences (NDPCHS) and Department of Oncology at the University of Oxford, report that cancer data collected by national cancer registries is comparable to the data gathered directly by researchers in clinical studies. This could make cancer research much easier and less expensive in the future.
COVID-19 vaccines are safe and effective for people with blood cancer, study finds
Cancer QResearch
15 February 2024
A new study from researchers in our department provides reassuring evidence that COVID-19 vaccines are safe and effective for people with blood cancers, despite their vulnerable immune systems.
New model predicts risk of developing and dying from breast cancer within 10 years to aid personalised screening
Cancer QResearch
24 August 2023
A team of researchers at the University of Oxford, led by the Nuffield Department of Primary Care Health Sciences, have developed a new model that reliably predicts a woman's likelihood of developing and then dying of breast cancer within a decade.
New study offers hope in early detection of oesophageal cancer
Cancer Digital health & innovation QResearch
15 August 2023
Researchers at the Nuffield Department of Primary Care Health Sciences have developed a new tool to predict people’s risks of getting oesophageal cancer in the next ten years.
NDPCHS Joins Major NIHR Policy Research Programme on Cancer Research
Cancer Policy & health systems
4 August 2023
The NIHR unveils a significant investment in its Policy Research Units, with a spotlight on early cancer detection. Led by experts from Oxford and UCL, this initiative aims to transform research into actionable policies, targeting the NHS's ambitious goal of early diagnosis for 3 out of 4 cancer patients by 2028.
Multi-cancer blood test showed ‘real promise’ in NHS trial
Cancer Clinical trials
2 June 2023
An NHS trial of a new blood test for more than 50 types of cancer, led by the University of Oxford, correctly revealed two out of every three cancers among over 5,000 people who had visited their GP with suspected symptoms, in England or Wales. The test also correctly identified the original site of cancer in 85% of those cases.
New Oxford and Nottingham developed tool uses existing health records to predict people’s risk of developing lung cancer within the next 10 years.
Cancer Digital health & innovation Infection, Respiratory and Acute Care QResearch
6 April 2023
A team of researchers from the University of Oxford and the University of Nottingham have developed a new tool, called ‘CanPredict’, able to identify the people most at risk of developing lung cancer over the next 10 years, and put them forward for screening tests earlier, saving time, money and, most importantly, lives.
Annual Cancer and Primary Care Research International Network (Ca-PRI) Conference
Cancer
31 March 2023
The Cancer Research Group recently hosted the 14th Annual Cancer and Primary Care Research International Network (Ca-PRI) Conference at Worcester College over 23rd and 24th of March. We were joined for a jam packed 2 days by a record-breaking number of delegates from 14 countries across 4 continents who were enthusiastic to attend the first face-to-face Ca-PRI Conference since 2019.
Inequalities in COVID-19 vaccine uptake remain among people with blood cancers
COVID-19 Cancer Infection, Respiratory and Acute Care QResearch
15 February 2023
People with blood cancers are among the most clinically vulnerable individuals to COVID-19 in the UK, and a new analysis of over 12 million patient health records has revealed inequalities in COVID-19 vaccine uptake among this group.
Pancreatic cancer could be diagnosed up to three years earlier
Cancer Infection, Respiratory and Acute Care
2 November 2022
Pancreatic cancer could be identified in patients up to three years earlier than current diagnoses, new research suggests. Weight loss and increasing blood glucose levels are early indicators of pancreatic cancer and could lead to a more timely diagnosis, helping to improve survival rates.
Research from Nuffield Department of Primary Care Health Sciences contributes to new guidelines on faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer
Cancer Health behaviours
4 August 2022
The joint guideline from the Association of Coloproctology of Great Britain and Ireland (ACPGBI) and the British Society of Gastroenterology (BSG) provides a clear strategy for the use of FIT in the colorectal cancer diagnostic pathway.
Measured weight loss associates with an increased risk of a cancer diagnosis
Cancer Health behaviours
4 August 2022
Weight loss is a sign of undiagnosed cancer regardless of the interval over which it occurs.
Time-varying nature of clinical risk factors for pancreatic cancer may aid earlier diagnosis, finds new study
Cancer QResearch
29 June 2022
Body mass index, blood tests, comorbidities and medication use are temporally associated with cancer risk in the three years before a pancreatic cancer diagnosis.
Blood tests provide no additional information to FIT alone when prioritising patients for colorectal cancer referral
Cancer
15 March 2022
Faecal immunochemical testing (FIT) alone leads to the identification of the same number of patients with colorectal cancer as more complicated approaches that combine the FIT result with the results of commonly used blood tests.
Department Researchers work highlighted at NCRI festival: Fewer cases of children’s cancer picked up during COVID pandemic
COVID-19 Cancer Infection, Respiratory and Acute Care QResearch
12 November 2021
A study of cancer in children and young adults in England has found that fewer patients were diagnosed during the COVID-19 pandemic. The research, presented at the NCRI Festival, also shows that children who were diagnosed with cancer during the first wave of the pandemic were more likely to have been admitted to intensive care prior to their diagnosis.
Department Researchers work highlighted at NCRI festival: New symptoms identified that could help doctors diagnose pancreatic cancer
Cancer Infection, Respiratory and Acute Care QResearch
8 November 2021
Researchers have identified a series of symptoms associated with pancreatic cancer, including two previously unrecognised symptoms – feeling thirsty and having dark urine – in a study presented today (Monday, 8th Jan) at the NCRI Festival.
Pancreatic cancer early detection funds awarded to department researchers
Cancer QResearch
19 October 2021
Dr Pui San Tan and Professor Julia Hippisley-Cox receive a Research Innovation Award from Pancreatic Cancer UK to develop a risk tool to predict pancreatic cancer in patients with diabetes.
Department cancer-risk research featured in special edition of PLOS Medicine focussed on advances in early cancer detection
Cancer Digital health & innovation Infection, Respiratory and Acute Care
2 September 2021
The research, led by researchers at the Nuffield Department of Primary Care Health Sciences, is highlighted in a special collection of studies that focus on early cancer detection, hailed by the Editors as “cutting edge, and potentially scalable, innovations that have the potential to inform research, policy, and clinical cancer management.”
New clinical prediction tools for myeloma
Cancer Infection, Respiratory and Acute Care
13 April 2021
Thousands of patients may have undiagnosed and untreated bowel cancer due to COVID-19 disruption
COVID-19 Cancer Policy & health systems
15 January 2021
A new study led by the University of Oxford has found that since the first coronavirus lockdown the number of people diagnosed with bowel cancer in England has fallen sharply, with a deficit persisting up to October 2020.