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Spending by the National Health Service continues to rise. To continue to offer safe and effective health care, we need to find ways to improve efficiency and reduce costs. Children make up one-fifth of the UK population and 10% of the general practice workload. If we can find ways to improve efficiency in paediatric care, everyone could benefit, most of all children and their parents.
Common heart medication ineffective for kidney disease patients, new study finds
Cardiovascular & metabolic
1 October 2024
Researchers from NDPCHS have found that a widely used heart medication, spironolactone, does not help prevent heart problems in people with chronic kidney disease (CKD). The study, published in Nature Medicine, found no significant benefit from the drug and highlighted safety concerns that led many patients to stop the treatment.
World hypertension day: How we’re tackling high blood pressure from pregnancy to later life
Cardiovascular & metabolic Digital health & innovation Public engagement & involvement
17 May 2024
For World Hypertension Day 2024, discover three of our innovative studies – SNAP2, SHIP, and OPTIMISE 2 – aiming to improve blood pressure management across the life cycle through technology and patient involvement.
New heart disease calculator could save lives by identifying high-risk patients missed by current tools
Cardiovascular & metabolic
18 April 2024
Collaborative research, led from NDPCHS and published today in Nature Medicine, has developed a new tool called QR4 that more accurately predicts an individual's 10-year risk of cardiovascular diseases, like heart disease and stroke, particularly identifying high-risk patients that current prediction tools miss.
New Oxford Study Shows Brief Sleep Therapy Delivered by Nurses Improves Insomnia
Cardiovascular & metabolic Clinical trials Policy & health systems
11 August 2023
Researchers from the University of Oxford have found that a brief form of cognitive behavioural therapy (CBT) for insomnia, delivered by nurses in GP surgeries, significantly improves sleep and quality of life compared to sleep hygiene alone.
Rapid weight loss found to be safe and helpful for people with liver disease, Oxford trial reveals
Cardiovascular & metabolic Clinical trials Health behaviours
28 June 2023
A clinical trial, led by a team at NDPCHS, has shown that a three-month rapid weight loss programme was not only safe but also effective in reducing the severity of a liver disease called non-alcoholic steatohepatitis (NASH) with liver fibrosis.
Food industry shows ‘stalled progress’ to reduce salt intakes, new Oxford-led analysis finds
Cardiovascular & metabolic Policy & health systems
20 October 2022
New research led from the Nuffield Department of Primary Care Health Sciences has shown that, overall, the average salt content of food products sold at supermarkets has not changed between 2015 and 2020. The results also showed that for certain products (ready meals, pizzas and soups) the volume of salt sold increased during this time.
Night-time blood pressure assessment is important in diagnosing hypertension and preventing cardiovascular disease, study reveals
Cardiovascular & metabolic Health Services Research
22 September 2022
Around 15% of people aged 40-75 may have a form of undiagnosed high blood pressure (hypertension) that occurs only at night-time. Because they do not know about this, and therefore are not being treated for it, they are at a higher risk of cardiovascular disease such as stroke, heart failure, and even death, suggests new research from the University of Oxford.
COVID-19 infection more likely than vaccines to cause rare cardiovascular complications
COVID-19 Cardiovascular & metabolic QResearch
16 December 2021
Led by the University of Oxford, a team of UK-based researchers have today reported results of the largest ever study to compare the risks of cardiovascular events, such as myocarditis, pericarditis, and cardiac arrhythmia, between different vaccines and COVID-19 infection, and the first to investigate the association between cardiac events and the Oxford-AstraZeneca vaccine.
Reduction in UK red and processed meat intake, but more needed to meet our climate targets
Cardiovascular & metabolic Policy & health systems
8 October 2021
Daily meat consumption in the UK has decreased by approximately 17.4g per person per day – just under a 17% reduction – in the last decade finds new research from the University of Oxford. Between 2008/09 and 2018/19 people in the UK reduced both the amount of red and processed meat they eat, while slightly increasing their white meat consumption. Yet, this reduction is significantly less than the 30% reduction the National Food Strategy has recently called for within the next ten years.
Benefit-to-harm balance of statins for healthy adults "generally favourable", suggests Oxford-led research
Cardiovascular & metabolic DPhil
15 July 2021
Statins are associated with a small increased risk of side effects in patients without a history of heart disease, but these effects are mild compared with the potential benefits of treatment in preventing major cardiovascular events, finds a study led by Oxford University researchers.
Foods associated with an increased risk of cardiovascular disease and death in middle-age identified
Cardiovascular & metabolic Health behaviours
22 April 2021
Two common dietary patterns identified in British adults, which include high intakes of chocolate and confectionary, may be associated with an increased risk of cardiovascular disease and death in middle-age, according to a study published in the open access journal BMC Medicine by Oxford University researchers.
Risk of severe COVID-19 from asthma and other respiratory diseases may be only modestly increased, new analysis suggests
COVID-19 Cardiovascular & metabolic Infection, Respiratory and Acute Care
2 April 2021
People with asthma have only a modestly increased risk of developing severe Covid-19 and requiring admission to hospital from the illness, finds an analysis of 8.3 million electronic health care records in England led by University of Oxford researchers.
No link between blood pressure drugs and falls, finds study
Cardiovascular & metabolic
10 February 2021
While treatment for high blood pressure is not associated with falls, there is some evidence to suggest patients who take blood pressure lowering medications may be more likely to faint or suffer kidney problems which lead to hospital admission, finds a study led by University of Oxford researchers.
Remote, online support for blood pressure management at home is effective and low-cost
Cardiovascular & metabolic Digital health & innovation
20 January 2021
At-home blood pressure monitoring using a web-based system offering personalised support and linked to a remote healthcare professional can result in better hypertension management than face-to-face consultations, finds a study led by University of Oxford, Bristol and Southampton researchers.
Difference in blood pressure between arms linked to greater death risk
Cardiovascular & metabolic
4 January 2021
Robust evidence from a large international study confirms that a difference in blood pressure readings between arms is linked to greater risk of heart attack, stroke and death.
Gender differences in heart failure care need to be addressed
Cardiovascular & metabolic Infection, Respiratory and Acute Care
30 September 2020
Women tend to be diagnosed with heart failure five years older than men, but have a better prognosis, finds research published in the European Journal of Heart Failure.
Less is more? Deprescribing blood pressure lowering medications is safe in the short-term in older people with frailty and multiple long-term conditions
Cardiovascular & metabolic Clinical trials
26 May 2020
Almost half of chronic kidney disease is unrecognised
Cardiovascular & metabolic Clinical trials
11 February 2020
More than 18 percent of over 60's have chronic kidney disease (CKD), around 44 percent of whom are undiagnosed without screening, finds a study led by Oxford University researchers.
Black and ethnic minority people face inequality in diabetes treatment
Cardiovascular & metabolic Infection, Respiratory and Acute Care
7 October 2019
Finger-prick blood test at GP surgery could safely reduce antibiotic use in patients with chronic obstructive pulmonary disease
Cardiovascular & metabolic Clinical trials Infection, Respiratory and Acute Care
11 July 2019