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Nick Kane
Benefit-to-harm balance of statins for healthy adults "generally favourable", suggests Oxford-led research
15 July 2021
Statins are associated with a small increased risk of side effects in patients without a history of heart disease, but these effects are mild compared with the potential benefits of treatment in preventing major cardiovascular events, finds a study led by Oxford University researchers.
PRINCIPLE trial 'highly commended' for innovative use of health data
5 July 2021
The PRINCIPLE trial has been highly commended at the Health Data Research UK Awards for the way in which patient data is utilised so participants are contacted about the trial soon after receiving a positive test result.
Long COVID cases appear to be under-reported in NHS GP records, shows OpenSAFELY analysis
30 June 2021
Good data on Long COVID will be crucial for research into the prevalence of Long COVID, its causes and consequences, and to plan services effectively, say researchers following their analysis of 96% of electronic healthcare records in England using the OpenSAFELY platform.
Ivermectin to be investigated as a possible treatment for COVID-19 in the PRINCIPLE trial
23 June 2021
From today, ivermectin is being investigated in the UK as part of the Platform Randomised Trial of Treatments in the Community for Epidemic and Pandemic Illnesses (PRINCIPLE), the world’s largest clinical trial of possible COVID-19 treatments for recovery at home and in other non-hospital settings.
Ethnic minority children may be disproportionately impacted by COVID-19, suggests analysis
21 June 2021
There are higher proportions of ethnic minority children in England testing positive for COVID-19 than white children, with Asian children more likely to be admitted to hospital with the illness, finds an observational analysis of 2.6 million healthcare records led by Oxford University researchers.
Celebrating International Clinical Trials Day 2021
20 May 2021
Each year, International Clinical Trials Day recognises the people who conduct clinical trials, giving our community a chance to say thank you for everything they do to improve public health. This year our trials unit staff are sharing what makes them proud to be part of Oxford’s Primary Care Clinical Trials Unit.
New study shows potential link between bodyweight and risk of severe COVID-19, especially for younger adults
29 April 2021
The first large study to report the effect of bodyweight on risk of worse outcomes from COVID-19 across the full range of body mass index (BMI) is published today in The Lancet Diabetes and Endocrinology journal.
Foods associated with an increased risk of cardiovascular disease and death in middle-age identified
22 April 2021
Two common dietary patterns identified in British adults, which include high intakes of chocolate and confectionary, may be associated with an increased risk of cardiovascular disease and death in middle-age, according to a study published in the open access journal BMC Medicine by Oxford University researchers.
Asthma drug budesonide shortens recovery time in non-hospitalised patients with COVID-19
12 April 2021
Inhaled budesonide, a common corticosteroid, is the world's first widely available, inexpensive drug found to shorten recovery times in COVID-19 patients aged over 50 who are treated at home and in other community settings, reports the PRINCIPLE trial in 1,779 participants. As of today, the treatment is available in UK primary care on a case-by-case basis.
Favipiravir to be investigated as a possible COVID-19 treatment for at-home recovery in the PRINCIPLE trial
8 April 2021
Could the antiviral favipiravir help transform COVID-19 into an illness that can be successfully treated by general practitioners?
Risk of severe COVID-19 from asthma and other respiratory diseases may be only modestly increased, new analysis suggests
2 April 2021
People with asthma have only a modestly increased risk of developing severe Covid-19 and requiring admission to hospital from the illness, finds an analysis of 8.3 million electronic health care records in England led by University of Oxford researchers.
Five simple steps to effective opportunistic weight loss conversations in family practice
26 March 2021
Five simple communication changes could enable doctors to have more equitable and effective conversations about weight loss, finds new research from the University of Oxford and Loughborough University. With obesity as one of the few modifiable risk factors for developing severe COVID, the findings are especially important during the current pandemic.