News and opinion

Photo of a man being given a vaccination by a male healthcare professional

COVID-19 vaccine protects people of all body weights from hospitalisation and death, a study of 9 million adults in England finds

1 July 2022

Two doses of the COVID-19 vaccine are effective against severe disease for people who are underweight, overweight, or who have obesity, finds new research published in The Lancet Diabetes and Endocrinology, led by researchers at the University of Oxford.

A time line image of the milestones that have been reached in the first two years of the PRINCIPLE Trial

The PRINCIPLE Trial - two years on

16 May 2022

The PRINCIPLE Trial has led the way in evaluating treatments for COVID-19 in the community over the last two years.

FHS student, Harrison France, in field of sunflowers

Congratulations to FHS student, Harrison France, on receiving 1st place in IUPHAR Student Research Poster Competition 2022

22 April 2022

Final Honours student, Harrison France, from the Nuffield Department of Primary Care Health Science and the Centre for Evidence-Based Medicine, has recently been awarded 1st place in the the IUPHAR (International Union of Basic and Clinical Pharmacology) Student Research Poster Competition 2022 by the British Pharmacological Society, for his research on preventable deaths involving medicines.

Primary care research nurses nominated for OUH Award

13 April 2022

Congratulations to the amazing team of research nurses working in the Primary Care Clinical Trials Unit who have been shortlisted as finalists in the Oxford University Hospitals NHS Foundation Trust Staff Recognition Awards 2021.

A photo of the paxlovid covid-19 treatment packaging.

New antiviral, Paxlovid, added to PANORAMIC study

12 April 2022

From today, the antiviral treatment Paxlovid has been included in the national PANORAMIC study, the UK’s fastest ever recruiting clinical trial of its kind, run by the Nuffield Department of Primary Care Health Sciences and supported by the National Institute for Health and Care research (NIHR).

Thank you in different languages from the PRINCIPLE trial

10,000 people join the PRINCIPLE Trial – A huge ‘Thank You’ from us all.

4 April 2022

10,000 people have joined the PRINCIPLE Trial over the last two years and we want to say a big ‘Thank You’ to them all for their amazing contribution to testing treatments for COVID-19 in the community.

Dark blue background, text reads: We couldn't have done this without you.

PANORAMIC hits the 20,000 participant milestone

31 March 2022

The world’s largest study of community-based treatments for acute COVID-19 has reached a world-first, historic milestone: over twenty thousand participants from across the UK have now taken part in the PANORAMIC trial.

COVID-19 infection more likely than vaccines to cause rare cardiovascular complications

16 December 2021

Led by the University of Oxford, a team of UK-based researchers have today reported results of the largest ever study to compare the risks of cardiovascular events, such as myocarditis, pericarditis, and cardiac arrhythmia, between different vaccines and COVID-19 infection, and the first to investigate the association between cardiac events and the Oxford-AstraZeneca vaccine.

A graphic containing details of the study and signposting to www.panoramictrtial.org for more information.

Recruitment begins for national community COVID-19 antiviral trial

8 December 2021

Researchers from the University of Oxford have today started recruiting participants for a first-of-its-kind clinical trial to test novel antiviral COVID-19 treatments for use early on in the illness by people in the community with COVID-19 and those who are at higher risk of complications – partnering with the National Institute for Health Research (NIHR) and working with colleagues in several UK universities, and the NHS UK-wide.

Department Researchers work highlighted at NCRI festival: Fewer cases of children’s cancer picked up during COVID pandemic

12 November 2021

A study of cancer in children and young adults in England has found that fewer patients were diagnosed during the COVID-19 pandemic. The research, presented at the NCRI Festival, also shows that children who were diagnosed with cancer during the first wave of the pandemic were more likely to have been admitted to intensive care prior to their diagnosis.

PCR cycle threshold may be key to predicting infectiousness of people with asymptomatic and pre-symptomatic COVID-19, suggests new review.

1 November 2021

An international team of researchers, led from Centre for Evidence-based Medicine based in the Nuffield Department of Primary Care Health Sciences, University of Oxford, and funded by the World Health Organization and the National Institute for Health Research School for Primary Care Research, have today announced the findings from the most complete analysis of high-quality covid transmission studies in asymptomatic and pre-symptomatic people to date.

Department awarded funding to complete community COVID-19 antiviral trial

26 October 2021

Researchers from the Nuffield Department of Primary Care Health Sciences, University of Oxford, have today announced that they have been awarded funding through the National Institute for Health Research (NIHR) to work with several UK universities and carry out a first-of-its-kind clinical trial, testing novel antiviral COVID-19 treatments for use early on in the illness by people in the community with COVID-19 who are at higher risk of complications.

COVID-19 infection has greater risk of causing very rare neurological events than vaccines

25 October 2021

Researchers from across the UK, led by the University of Oxford, have today reported on the risks of developing neurological complications following a positive COVID-19 PCR test, or a first dose of either the Oxford-AstraZeneca or Pfizer-BioNTech COVID-19 vaccinations.

Department led Covid research partnership wins national computing innovation award

11 October 2021

A collaboration which used anonymised GP records to identify 1.5m people most at risk from Covid-19 and prioritise them for vaccination has won the prestigious John Perry Prize for computing innovation in primary care.

Smoking associated with higher risk of death and hospitalisation with COVID-19

28 September 2021

Smoking is highly likely to worsen the severity of COVID-19 and the risk of dying with the infection, finds a large study led by researchers from the University of Oxford and published online in the respiratory journal Thorax.

QCovid highly commended for ‘best use of technology in Patient Safety’ at the 2021 HSJ Patient Safety Awards

23 September 2021

Professor Julia Hippisley-Cox and her team have been Highly Commended in the ‘Best use of technology in Patient Safety’ category for the QCovid risk calculator at this year’s Health Service Journal Patient Safety Awards.

A person being vaccinated against covid-19

Vaccinated groups at highest risk of Covid-19 hospitalisation and death identified using new QCovid tool

20 September 2021

New algorithm predicts those most at risk of serious Covid-19 outcomes from 14 or more days after second vaccination dose, when substantial immunity is expected to have developed Authors hope this new risk tool will allow those who perceive risk to be high to make more informed decisions regarding shielding and potentially inform policy and clinical decisions on booster vaccine doses and monoclonal antibodies

Blog: Opinions from our research and teaching

Retracted publications on COVID-19 and SARS-CoV-2: transparency in research

7 hours and 9 minutes ago

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