From today, ivermectin is being investigated in the UK as part of the Platform Randomised Trial of Treatments in the Community for Epidemic and Pandemic Illnesses (PRINCIPLE), the world\u2019s largest clinical trial of possible COVID-19 treatments for recovery at home and in other non-hospital settings.
There are higher proportions of ethnic minority children in England testing positive for COVID-19 than white children, with Asian children more likely to be admitted to hospital with the illness, finds an observational analysis of 2.6 million healthcare records led by Oxford University researchers.
Each year, International Clinical Trials Day recognises the people who conduct clinical trials, giving our community a chance to say thank you for everything they do to improve public health. This year our trials unit staff are sharing what makes them proud to be part of Oxford\u2019s Primary Care Clinical Trials Unit.
The first large study to report the effect of bodyweight on risk of worse outcomes from COVID-19 across the full range of body mass index (BMI) is published today in The Lancet Diabetes and Endocrinology journal.
Two common dietary patterns identified in British adults, which include high intakes of chocolate and confectionary, may be associated with an increased risk of cardiovascular disease and death in middle-age, according to a study published in the open access journal BMC Medicine by Oxford University researchers.
Inhaled budesonide, a common corticosteroid, is the world's first widely available, inexpensive drug found to shorten recovery times in COVID-19 patients aged over 50 who are treated at home and in other community settings, reports the PRINCIPLE trial in 1,779 participants. As of today, the treatment is available in UK primary care on a case-by-case basis.
People with asthma have only a modestly increased risk of developing severe Covid-19 and requiring admission to hospital from the illness, finds an analysis of 8.3 million electronic health care records in England led by University of Oxford researchers.
Five simple communication changes could enable doctors to have more equitable and effective conversations about weight loss, finds new research from the University of Oxford and Loughborough University. With obesity as one of the few modifiable risk factors for developing severe COVID, the findings are especially important during the current pandemic.
Three articles, led by Oxford researchers in the department, including three DPhil students, make the top 10 list for \r\nthe most read open research articles in the BJGP Open for 2020 - including number one.
From today, the UK\u2019s national priority platform trial of Covid-19 treatments for recovery at home launches its investigation of the gout drug colchicine, and expands for the first time to include adults of any age.
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