We co-ordinate studies in three main themes, which are aligned with the departmental priorities on infectious diseases, cardiovascular and metabolic disease and health behaviours in addition to other topics of major national and international importance. Find out more about our current portfolio below, or our completed studies.
Cardiovascular & metabolic:
Our clinical research aims to find out which patients are at risk of chronic kidney disease, how their cardiovascular health is affected by this and how screening and monitoring can help.
Infections & acute care:
We are running trials to investigate treatments other than antibiotics for patients presenting with common cough and cold symptoms. This may give GPs and patients treatment options other than antibiotics to help relieve symptoms for these common illnesses.
Health behaviours & other conditions:
We conduct clinical trials offering support to patients regarding weight management and smoking cessation. Better support for behaviour changes can prevent the development of more serious health problems resulting in long-term benefits for patients and the NHS.
Cardiovascular & metabolic
The BUMP trial is testing whether monitoring blood pressure at home during pregnancy can help the early detection of hypertension and pre-eclampsia.
An observational study to determine the incidence of venous thromboembolism among care home residents
Optimising Management of Patients with Heart Failure with Preserved Ejection Fraction in Primary Care
Randomised clinical trial of Bococizumab in subjects with hyperlipidemia or mixed dyslipidemia at risk of cardiovascular events.
Infections & acute care
d-MannosE to prevent Recurrent urine InfecTions. Using a naturally occurring sugar d-Mannose to treat recurrent urinary tract infections.
Point of care testing to target antibiotics for chronic obstructive pulmonary disease exacerbations
Alternative treatments of adult female urinary tract infection: a double blind, placebo controlled, factorial randomised trial
A pilot study on the effects of adding c-reactive protein (CRP) point-of-care testing in the management of acutely ill children in primary care
Health behaviours & other conditions
Health professional Administered Brief Insomnia Therapy (HABIT) trial. A pragmatic, multicentre, randomised controlled trial comparing nurse delivered sleep restriction therapy for insomnia disorder to sleep hygiene in primary care.
Brief interventions to support the management of smoking in primary care: a randomised controlled trial
The aim of the study is to investigate whether Health Trainer support is better at helping people to quit smoking for longer, compared with existing support.