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Trial portfolio

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We co-ordinate studies in three main themes, which are aligned with the departmental priorities on infectious diseases, cardiovascular and metabolic disease and health behaviours in addition to other topics of major national and international importance. Find out more about our current portfolio below, or our completed studies.

Cardiovascular & metabolic

Our clinical research aims to find out which patients are at risk of chronic kidney disease, how their cardiovascular health is affected by this and how screening and monitoring can help.

Infections & acute care

We are running trials to investigate treatments other than antibiotics for patients presenting with common cough and cold symptoms. This may give GPs and patients treatment options other than antibiotics to help relieve symptoms for these common illnesses.

Health behaviours & other conditions

We conduct clinical trials offering support to patients regarding weight management and smoking cessation. Better support for behaviour changes can prevent the development of more serious health problems resulting in long-term benefits for patients and the NHS.

  • BARACK-D

    Benefits of aldosterone receptor antagonism in chronic kidney disease

  • COMET

    Near-patient testing to guide COPD maintenance treatment in primary care

  • TASMINH4

    Telemonitoring and/or self-monitoring of blood pressure in hypertension

  • V-TEC

    An observational study to determine the incidence of venous thromboembolism among care home residents

  • FORM -2C

    Frequency of renal monitoring - cystatin-C and creatinine study

  • EDGE-COPD

    Self management and support programme (EDGE) for COPD

  • HOME-BP

    Home and online management and evaluation of blood pressure

  • OxRen

    Oxford renal longitudinal cohort study

  • OPTiMISE

    OPtimising Treatment for MIld Systolic hypertension in the Elderly

  • POC HbA1c

    Introducing point-of-care testing into primary care

  • SNAP-HT

    Self-management of postnatal anti-hypertensive treatment trial development pilot study

  • SPIRE

    Randomised clinical trial of Bococizumab in subjects with hyperlipidemia or mixed dyslipidemia at risk of cardiovascular events.

  • StAR-D

    SMS supporting treatment for people with type 2 diabetes

In set-up

BUMP RCT

UDIP

OXREN II

  • ALIC4E

    Antivirals for influenza like illness? An RCT of clinical and cost effectiveness in primary care

  • ARCHIE

    The early use of antibiotics for ‘at risk’ children with influenza

  • ATAFUTI

    Alternative treatments of adult female urinary tract infection: a double blind, placebo controlled, factorial randomised trial

  • CONDUCT

    Can urine collection devices reduce the chances of contamination?

  • CRP pilot

    A pilot study on the effects of adding c-reactive protein (CRP) point-of-care testing in the management of acutely ill children in primary care

  • HEAT

    Helicobacter eradication to prevent ulcer bleeding in aspirin users trial

  • MERMAIDS

    Acute respiratory infections in adults

  • PACE

    Point of care testing to target antibiotics for chronic obstructive pulmonary disease exacerbations

  • PRINCESS

    Probiotics to reduce infections in care home residents, the PRINCESS trial

  • RIVET

    Re-inventing influenza vaccine efficacy trials


  • BWeL

    Testing a brief intervention for weight management in primary care

  • CANDID

    Cancer diagnosis decision rules

  • DROPLET

    Doctor Referral of Overweight People to Low Energy Treatment

  • POWeR2

    Positive online weight reduction 2

  • Pre-loading

    Nicotine patch preloading for smoking cessation

  • WRAP

    Weight loss referrals for adults in primary care