Trial portfolio
We co-ordinate studies in three main themes, which are aligned with the departmental priorities on infectious diseases, cardiovascular and metabolic disease and health behaviours in addition to other topics of major national and international importance. Find out more about our current portfolio below, or our completed studies.
Cardiovascular & metabolic:
Our clinical research aims to find out which patients are at risk of chronic kidney disease, how their cardiovascular health is affected by this and how screening and monitoring can help.
Infections & acute care:
We are running trials to investigate treatments other than antibiotics for patients presenting with common cough and cold symptoms. This may give GPs and patients treatment options other than antibiotics to help relieve symptoms for these common illnesses.
Health behaviours & other conditions:
We conduct clinical trials offering support to patients regarding weight management and smoking cessation. Better support for behaviour changes can prevent the development of more serious health problems resulting in long-term benefits for patients and the NHS.
Cardiovascular & metabolic
-
BARACK-D
Benefits of aldosterone receptor antagonism in chronic kidney disease
-
COMET
Near-patient testing to guide COPD maintenance treatment in primary care
-
FORM -2C
Frequency of renal monitoring - cystatin-C and creatinine study
-
SNAP-HT
Self-management of postnatal anti-hypertensive treatment trial development pilot study
-
SPIRE
Randomised clinical trial of Bococizumab in subjects with hyperlipidemia or mixed dyslipidemia at risk of cardiovascular events.
-
StAR-2D
SMS supporting treatment for people with type 2 diabetes
-
TASMINH4
Telemonitoring and/or self-monitoring of blood pressure in hypertension
-
V-TEC
An observational study to determine the incidence of venous thromboembolism among care home residents
-
The BUMP Trial
Blood pressure monitoring in pregnancy
-
HOME-BP
Home and online management and evaluation of blood pressure
-
OxRen
Oxford renal longitudinal cohort study
-
OPTiMISE
OPtimising Treatment for MIld Systolic hypertension in the Elderly
In set-up
UDIP
OXREN II
Infections & acute care
-
ALIC4E
Antivirals for influenza like illness? An RCT of clinical and cost effectiveness in primary care
-
ARCHIE
The early use of antibiotics for ‘at risk’ children with influenza
-
ATAFUTI
Alternative treatments of adult female urinary tract infection: a double blind, placebo controlled, factorial randomised trial
-
CONDUCT
Can urine collection devices reduce the chances of contamination?
-
CRP pilot
A pilot study on the effects of adding c-reactive protein (CRP) point-of-care testing in the management of acutely ill children in primary care
-
HEAT
Helicobacter eradication to prevent ulcer bleeding in aspirin users trial
-
MERMAIDS
Acute respiratory infections in adults
-
PACE
Point of care testing to target antibiotics for chronic obstructive pulmonary disease exacerbations
-
PRINCESS
Probiotics to reduce infections in care home residents, the PRINCESS trial
-
RIVET
Re-inventing influenza vaccine efficacy trials
Health behaviours & other conditions
-
BWeL
Testing a brief intervention for weight management in primary care
-
CANDID
Cancer diagnosis decision rules
-
DROPLET
Doctor Referral of Overweight People to Low Energy Treatment
-
POWeR2
Positive online weight reduction 2
-
Pre-loading
Nicotine patch preloading for smoking cessation
-
WRAP
Weight loss referrals for adults in primary care
In set-up
MaSC