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Oxford renal longitudinal cohort study

A prospective population based study of chronic kidney disease (CKD) to examine the optimal methods for screening, cardiovascular risk prediction and interventions to prevent declining kidney function. This study will estimate prevalence, incidence and progression of CKD from a sample within Oxfordshire demographically representative of the UK general population.

Background

Chronic kidney disease (CKD) is a worldwide health problem and increasing prevalence. Cardiovascular disease (CVD) is a major cause of morbidity and death in CKD with a different phenotype to the general CVD population. There have been relatively few studies detailing the prevalence, incidence and progression of CKD in the UK and no studies collecting primary data in the utility of screening for CKD in the general population.

Alternative renal biomarkers may have greater accuracy for cardiovascular risk stratification but their predictive role as assessed in prospective longitudinal cohort designed to elucidate the progression and prognosis for CKD during the various stages of the disease using a cohort with 10 years followup in the first instance.

 

Study Design: Longitudinal cohort study
Sponsor: University of Oxford
Chief Investigator: Professor Richard Hobbs, University of Oxford
Ethical Approval: 13/SC/0020    
Contact Details: oxren@phc.ox.ac.uk

Ox-Ren