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Nicotine patch preloading for smoking cessation

This study aims to examine the relative efficacy, safety and cost effectiveness of standard NHS stop-smoking treatment versus standard treatment plus nicotine patch worn for 4 weeks prior to quitting.                  

Background

People who try to stop smoking typically experience urges to smoke, often described as cravings, frequently in response to environmental cues associated with smoking (such as drinking alcohol). These urges decrease in intensity and frequency with time. The key to stopping smoking is to resist these urges. Effective medication for smoking cessation reduces the intensity of the urges, and this is the likely mechanism of action.

Study Design: Open label pragmatic randomised controlled trial.
Sponsor:  University of Oxford
Ethical Approval: 12/EM/0014     
Chief Investigator: Professor Paul Aveyard, University of Oxford
Contact Details: sarah.tearne@phc.ox.ac.uk

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