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Macrophages, a major component of innate immune defence, express a large repertoire of different classes of pattern recognition receptors and other surface antigens which determine the immunologic and homeostatic potential of these versatile cells. In the light of present knowledge of macrophage surface antigens, we discuss self versus nonself recognition, microbicidal effector functions and self tolerance in the innate immune system. © 2009 Landes Bioscience and Springer Science+Business Media.

Original publication

DOI

10.1007/978-1-4419-0901-5_1

Type

Journal article

Journal

Advances in Experimental Medicine and Biology

Publication Date

01/12/2009

Volume

653

Pages

1 - 14