Ailsa R Butler
Postdoctoral Researcher & Systematic Reviewer
I work with the Health Behaviours team in the Nuffield Department of Primary Care Health Sciences. I am working as principal investigator on an ARC funded project to determine the important questions for future research in the field of weight management and obesity. Our priority setting project, Priorities for Obesity and Weight-related Research (POWER), follows the general steps set out by the James Lind Alliance. We aim to gather and prioritise potential research questions via two online surveys and a workshop involving members of the public, researchers, healthcare and public health professionals, policy makers and the voluntary sector. The list of the research questions agreed upon will be widely shared.
I am working on a large evidence synthesis collating information from randomised controlled trials to explore and evaluate the long-term outcomes of behavioural weight management programmes in terms of weight regain and associated health outcomes. This project is funded by the British Heart Foundation and the National Institute for Health Research Oxford Biomedical Research Centre.
My background is in epidemiology, infectious disease modelling and public health policy. I have a DPhil in epidemiology, my thesis explored childhood vaccination schedules and used data to validate the use of mathematical models in this process. I worked Parliament for the All-Party Parliamentary Group on HIV/AIDS, in this role I linked medical and epidemiological research and information and the views experiences of the voluntary sector to Parliamentarians. As a Post-Doc at Imperial College I worked on a project to explore the effect of a proposed link between injectable hormonal contraception and susceptibility to HIV acquisition. While at Imperial College I have worked on systematic reviews on health behaviour linked to HIV spread and on time spent in different HIV stages.
Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening
Picco G. et al, (2019), Nature Communications, 10
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation
Brinkman AB. et al, (2019), Nature Communications, 10
Integration of transcriptional and mutational data simplifies the stratification of peripheral T-cell lymphoma
Maura F. et al, (2019), American Journal of Hematology, 94, 628 - 634
The circular RNome of primary breast cancer
Smid M. et al, (2019), Genome Research, 29, 356 - 366
Correction to: Landscape of somatic mutations in 560 breast cancer whole-genome sequences (Nature, (2016), 534, 7605, (47-54), 10.1038/nature17676)
Nik-Zainal S. et al, (2019), Nature, 566