Ann Van den Bruel
My research focuses on diagnostic tests.
Diagnostic tests help doctors to identify illnesses and other conditions so that patients may be treated or given a prognosis about the course of the illness. It is important to study the added value of tests because a better understanding leads to more efficient healthcare and better outcomes for patients.
Over the past years, I have worked mainly on the diagnosis of serious infections in children. More precisely I conducted a large-scale study in primary care to analyse the value of clinical features for this diagnosis. In addition, we looked at how laboratory tests can help with this diagnosis and how parents and doctors view the diagnostic process when a child is admitted to hospital with a serious infection. The results of these studies have been used in several guidelines including one on feverish children by NICE.
More generally, I have collaborated with colleagues in other studies on diagnostic tests, such as clinical features in patients with chest pain, ultrasound for patients with shoulder problems, exercise testing to identify coronary disease, etc.
In addition to research, I'm also involved in teaching for the Centre for Evidence Based Medicine and other institutions across Europe.
Early detection of multiple myeloma in primary care using blood tests: a case-control study in primary care.
Koshiaris C. et al, (2018), Br j gen pract, 68, e586 - e593
Improving the quality of point-of-care testing
Price CP. et al, (2018), Family practice, 35, 358 - 364
Quantifying intervals to diagnosis in myeloma: A systematic review and meta-analysis
Koshiaris C. et al, (2018), Bmj open, 8
Opportunities for earlier diagnosis of type 1 diabetes in children: A case-control study using routinely collected primary care records
Lee JJ. et al, (2018), Primary care diabetes, 12, 254 - 264
Point-of-care C reactive protein to identify serious infection in acutely ill children presenting to hospital: prospective cohort study.
Verbakel JY. et al, (2018), Arch dis child, 103, 420 - 426