Ann Van den Bruel
My research focuses on diagnostic tests.
Diagnostic tests help doctors to identify illnesses and other conditions so that patients may be treated or given a prognosis about the course of the illness. It is important to study the added value of tests because a better understanding leads to more efficient healthcare and better outcomes for patients.
Over the past years, I have worked mainly on the diagnosis of serious infections in children. More precisely I conducted a large-scale study in primary care to analyse the value of clinical features for this diagnosis. In addition, we looked at how laboratory tests can help with this diagnosis and how parents and doctors view the diagnostic process when a child is admitted to hospital with a serious infection. The results of these studies have been used in several guidelines including one on feverish children by NICE.
More generally, I have collaborated with colleagues in other studies on diagnostic tests, such as clinical features in patients with chest pain, ultrasound for patients with shoulder problems, exercise testing to identify coronary disease, etc.
In addition to research, I'm also involved in teaching for the Centre for Evidence Based Medicine and other institutions across Europe.
Point-of-care lactate testing for sepsis at presentation to health care: A systematic review of patient outcomes
Morris E. et al, (2017), British Journal of General Practice, 67, e859 - e870
Fractional exhaled nitric oxide monitoring in paediatric asthma management
Jones NR. et al, (2017), British Journal of General Practice, 67, 531 - 532
Predictors of pneumonia in lower respiratory tract infections: 3C prospective cough complication cohort study.
Moore M. et al, (2017), Eur Respir J, 50
Corticosteroids for sore throat: a clinical practice guideline
Aertgeerts B. et al, (2017), BMJ (Clinical research ed.), 358
Common evidence gaps in point-of-care diagnostic test evaluation: A review of horizon scan reports
Verbakel JY. et al, (2017), BMJ Open, 7