Research groups
Jennifer Hirst
BSc MSc DPhil
Senior Research Fellow
Epidemiologist
I am an experienced epidemiologist and methodologist leading studies on women's health and health inequalities. I am Principal Investigator on three grants on hormone replacement therapy (HRT) use and risks funded by the NIHR. One quantifying disparities in HRT prescribing in the UK and the others identifying socioeconomic and ethnic disparities in health outcomes: breast, endometrial and ovarian cancer, cardiovascular disease, dementia, osteoporosis and all-cause mortality with HRT use using electronic healthcare data. I am leading two work packages on a NIHR-funded programme grant on the safety of medication in pregnancy.
I have expertise in analyses of large electronic healthcare datasets (CPRD and QResearch), meta-analysis, managing UK-based and international multicentre clinical studies, clinical epidemiology and qualitative data collection and analysis.
Recent publications
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Benefits of aldosterone receptor antagonism in chronic kidney disease: the BARACK-D RCT.
Journal article
Hobbs FDR. et al, (2025), Health Technol Assess, 29, 1 - 130
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Ethnic disparities in lung cancer incidence and differences in diagnostic characteristics: a population-based cohort study in England
Journal article
Tzu-Hsuan Chen D. et al, (2025), The Lancet Regional Health - Europe, 48
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Correction to: Safety outcomes following COVID-19 vaccination and infection in 5.1 million children in England (Nature Communications, (2024), 15, 1, (3822), 10.1038/s41467-024-47745-z)
Journal article
Copland E. et al, (2024), Nature Communications, 15
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Predictive factors for the diagnosis of coeliac disease in children and young people in primary care: A systematic review and meta-analysis
Journal article
Farrier CE. et al, (2024), PLoS ONE, 19
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Safety outcomes following COVID-19 vaccination and infection in 5.1 million children in England
Journal article
Copland E. et al, (2024), Nature Communications, 15
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Uptake, effectiveness and safety of COVID-19 vaccines in individuals at clinical risk due to immunosuppressive drug therapy or transplantation procedures: a population-based cohort study in England
Journal article
Chen DTH. et al, (2024), BMC Medicine, 22
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Establishing the QResearch Pregnancy Register in the QResearch® database: methods and cohort description
Preprint
Snelling AJHL. et al, (2024)
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Outcomes for older people with screening detected versus existing chronic kidney disease: Cohort study with data linkage.
Journal article
Forbes AK. et al, (2024), BJGP Open
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Incidence of menstrual symptoms suggestive of possible endometriosis in adolescents: and variance in these by ethnicity and socio-economic status
Journal article
Dixon S. et al, (2024), The British journal of general practice : the journal of the Royal College of General Practitioners, 74
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A life-course approach to tackling noncommunicable diseases in women
Journal article
Carcel C. et al, (2024), Nature Medicine, 30, 51 - 60
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Low-dose spironolactone and cardiovascular outcomes in moderate stage chronic kidney disease: a randomized controlled trial
Journal article
Hobbs FDR. et al, (2024), Nature Medicine
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What is known about adolescent dysmenorrhoea in (and for) community health settings?
Journal article
Dixon S. et al, (2024), Frontiers in Reproductive Health, 6
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Uptake of COVID-19 vaccination in people with blood cancer: population-level cohort study of 12 million patients in England
Journal article
HIRST J., (2023), European Journal of Cancer
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Uptake, effectiveness and safety of COVID-19 vaccines in the immunocompromised population: A population-based cohort study in England
Preprint
Chen D. et al, (2023)
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PREDICTING INDIVIDUAL RISK OF MUSCLE DISORDERS IN PATIENTS ELIGIBLE FOR STATIN TREATMENT: STRATIFY-STATINMD MODEL DERIVATION USING DATA FROM ELECTRONIC HEALTH RECORDS
Journal article
Cai T. et al, (2022), Journal of hypertension, 40, e76 - e77