How to design a ROCI (Response Over Continuous Intervention) randomised trial: guidance and a case study.

Quartagno M., Ghorani E., Morris TP., Bern H., Clements MN., Walker AS., Carpenter JR., White IW., Pouwels KB., Seckl MJ., Parmar MK.

DOI

10.1186/s12874-026-02786-4

Type

Journal article

Publication Date

2026-04-25T00:00:00+00:00

Keywords

Clinical trials, Duration design, Non-inferiority, ROCI, Sample size

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