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Nargis Begum

BSc (Hons), MSc

Assistant Trial Manager

I work as part of the trial management team by supporting the trial manager with site set-up and recruitment. I am currently a member of the Cardiovascular and Renal Theme and work on the BARACK-D Trial, which investigates the use of Spironolactone in patients with Chronic Kidney Disease (CKD). CKD is a long-term impairment in kidney function and affects around 10% of the population. It is linked with an increased chance of developing heart disease and Spironolactone is an aldosterone receptor antagonist, which could offer cardio-protection and delay renal impairment.  

Prior to working at PC-CTU, I worked on Phase I/II dose-escalation oncology and immunotherapy studies at the Oncology Clinical Trials Office at Oxford University as a Clinical Trial Monitor. I also worked as a Data Manager and Trials Assistant on a large Phase III multi-arm multi-stage oncology trial at MRC CTU at UCL. I have also worked as a Research Administrator for the NIHR Clinical Research Network on observational non-CTIMP studies in neurodegenerative disorders and dementias.