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Wema Mtika

Medical Statistician

I am a Medical Statistician in the Primary Care Clinical Trials Unit (CTU) at the Nuffield Department of Primary Care Health Sciences, University of Oxford, working on the design, analysis, and reporting of clinical trials and hybrid trial–electronic health record (EHR) studies.

My expertise spans medical statistics, epidemiology, and data science, with interest in infectious diseases, large-scale electronic health records and nationwide study cohorts, evidence synthesis, health disparities, and global health, focusing on maternal, child and women's health. I have conducted extensive research in the UK, Brazil and Malawi, and led a global health research programme in Africa, Latin America, and Asia.

I am also committed to research translation, stakeholder engagement, and dissemination of evidence for policy and clinical practice. Outside my formal role, I mentor individuals interested in postgraduate study and academic careers.

Key research projects I have contributed to include:

  1. OPTIMISE2 Trial – Hybrid clinical trial–electronic health record (EHR) study evaluating deprescribing of antihypertensive treatment in older adults in England
  2. EVOLUTION Trial (EValuating a nOveL UTI dIagnOstic for aNtibiotic stewardship) – assessing whether use of a novel diagnostic tool reduces antibiotic prescribing for urinary tract infection without prolonging symptoms among women.
  3. Uptake, effectiveness and safety of COVID-19, influenza, and pertussis vaccination in Pregnancy using the QResearch – Large-scale EHR cohort studies in England.
  4. Inequalities in menopause symptoms and Hormone Replacement Therapy (HRT) uptake – systematic reviews, meta-analyses, and EHR analyses of over 2 million women in UK primary care.
  5. Disparities in maternal and infant mortality rates in Brazil – Nationwide epidemiological analyses
  6. Socioeconomic risk markers of dengue mortality in Brazil – Nationwide epidemiological analyses
  7. Environmental Sanitation Planning in Malawi –research on water, sanitation, and hygiene (WASH) in peri-urban areas
  8. Prevention of Mother to Child Transmission (PMTCT) in HIV/AIDS, Malawi