Common Data Models (CDMs) to Enhance International Big Data Analytics: A Diabetes Use Case to Compare Three CDMs
Liyanage H., Liaw ST., Jonnagaddala J., Hinton W., De Lusignan S.
Common data models (CDM) have enabled the simultaneous analysis of disparate and large data sources. A literature review identified three relevant CDMs: The Observational Medical Outcomes Partnership (OMOP) was the most cited; next the Sentinel; and then the Patient Centered Outcomes Research Institute (PCORI). We tested these three CDMs with fifteen pre-defined criteria for a diabetes cohort study use case, assessing the benefit (good diabetes control), risk (hypoglycaemia) and cost effectiveness of recently licenced medications. We found all three CDMs have a useful role in planning collaborative research and enhance analysis of data cross jurisdiction. However, the number of pre-defined criteria achieved by these three CDMs varied. OMOP met 14/15, Sentinel 13/15, and PCORI 10/15. None met the privacy level we specified, and most of the other gaps were clinical and cost outcome related data.