DECOVID: A UK Two-Center Harmonized Database of Acute Care Electronic Health Records for COVID-19 Research
Aslett LJM., Avramescu A., Bakewell N., Birds I., Bowler L., Camilleri MPJ., Chung SC., Clifton DA., Cohen SN., Constantine-Cooke N., Daub EG., Davidson S., Denaxas S., Diaz-Ordaz K., Feltbower R., Gallier S., Gardiner S., Gasperoni F., Goudie RJB., Green RE., Hall M., Holmes C., Hurst JR., Iles MM., Jorge J., Karoune E., Keogh R., King R., King R., Kirk PDW., Klapaukh R., Kouchaki S., Lai AG., Lea N., Leyrat C., Li K., Lilaonitkul W., Lu HY., Lyons T., Mallon AM., Manderson A., Margaritella N., Matteson J., Morley S., Nicholls H., O’Reilly M., Pagel C., Palmer E., Roberts J., Roberts TJ., Robertson DS., Robinson J., Rockenschaub P., Ruddle R., Sapey E., Santos L., Soltan AAS., Gao Smith F., Starr C., Strickson O., Su L., Tackney MS., Thygesen JH., Torralbo A., Turner A., Vallejos CA., Wang C., Whitaker K., Whitehouse T., Westhead DR., Wong WK., Wu Y., Yang L., Zou X.
The DECOVID database contains harmonized pseudonymized electronic health record (EHR) data on all adult (≥18 years old) patients presenting to two large, digitally mature centers in the United Kingdom between 1 January 2020 and 28 February 2021, with follow-up until at least 28 March 2021. The database was originally developed to support the COVID-19 response but is now available via the PIONEER data hub for researchers to explore a wide range of research questions, including exploratory analyses, risk factor assessment, prediction modeling, and comparative effectiveness studies. Raw data were extracted from local EHRs and transformed into a standardized form (Observational Health Data Sciences and Informatics-Common Data Model version 5.3.1). The database includes 165,420 patients across 256,804 hospital presentations. For these patients, highly granular data are available, including patient demographics, longitudinal vital signs, physiology, treatments, laboratory findings, clinical diagnoses, and outcomes. There are 10,030 patients with COVID-19, of whom 1472 died in hospital.