Implementing intensive control of blood glucose concentration and blood pressure in type 2 diabetes in England: Cost analysis (UKPDS 63)

Objective: To estimate the incremental cost of implementing policies for more intensive control of blood glucose concentration and blood pressure for all patients with type 2 diabetes in England. Design: Extrapolation of resource use and cost data derived from a randomised controlled trial. Setting: General practice, outpatient care, and inpatient care. Population: Trial population with diagnosed type 2 diabetes in England extrapolated to the population of England. Main outcome measures: Total costs based on use of healthcare resources including costs of management, treatment, and hospitalisation. Results: The incremental net annual cost of implementing more intensive control of blood glucose and blood pressure to all people with diagnosed type 2 diabetes in England is estimated to be £100.5m ($156m; C159m), which is equivalent to less than 1% of the proposed additional annual expenditure on the NHS in 2001-5. This estimate varied in sensitivity analyses from £67m to £121m. Conclusions: Policies to improve control of blood glucose and blood pressure of people with type 2 diabetes are effective in reducing complications associated with the disease and are also cost effective. The total cost represents a small fraction of the NHS's spending plans.