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Current clinical trials

CARE - Weight loss before bowel cancer surgery

ENDO-CARE - Weight loss before endometrial cancer surgery

Dimitrios Koutoukidis


Senior Research Fellow

  • NIHR Advanced Fellow
  • NIHR Oxford BRC Senior Research Fellow

Diet, Obesity, and Behavioural Sciences

I am a dietitian and my research focuses on testing how behavioural science can change dietary intake and improve outcomes for patients with obesity-related diseases, as well as exploring the mechanisms through which weight loss could exerts its effects.

I am currently funded by an NIHR Advanced Fellowship leading a programme of work that examines the role of intentional weight loss before cancer surgery. This work  focuses on assessing the feasibility of pre-operative diet-induced weight loss on post-operative complications in patients diagnosed with colorectal or endometrial cancer. This is complemented with  qualitative interviews, health economic modelling, and mechanistic studies. 

Prior to this, I built a programme of work on weight loss for the treatment of non-alcoholic fatty liver disease. This works used a variety of methodologies, including systematic reviews, meta-analyses, observational analyses, and clinical trials of low-energy diets. It showed that weight loss interventions meet the regulatory criteria for licencing pharmacotherapy for NAFLD and that low-energy diets are safe in an advanced form of NAFLD. It currently explores how the gut microbiome and the immune system might be implicated in these improvements and whether weight loss might be helpful in the treatment of liver cirrhosis. 

I am a member of the NIHR HS&DR funding committee. 

In 2017, I completed my PhD in Nutrition, Dietetics, and Behavioural Sciences at University College London funded by the UCL Grand Challenges. For my PhD, I adapted a theory-based behaviour change intervention for endometrial cancer survivors and piloted it in a randomised controlled trial. As a post-doc at UCL, I worked in two clinical trials of dietary and physical activity interventions in cancer survivors.  

Key publications

Recent publications

More publications