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Ly-Mee Yu

M.Sc., DPhil

Professor of Clinical Trials and Biostatistics

  • Deputy Director Academic (Primary Care Clinical Trials Unit)
  • Lead Trial Statistician

I joined the Department in 2013 after previously working at the Centre for Statistics in Medicine where I led a team of statisticians, collaborating on a variety of clinical studies (predominately randomised controlled trials) and supported numerous funding applications (e.g. NIHR, FP7, MRC, and Wellcome Trust).  I have over 27 years of experience as a medical statistician and specifically in clinical trials for the past 15 years.  I have worked in a wide range of clinical areas, including but not limited to, renal disease, behavioural medicine, vaccinology, cardiovascular medicine, infectious disease, surgery, allied health, mental health, neurosciences, respiratory, and orthopaedics.  I have published over 190 articles in peer-reviewed journals such as the Lancet, JAMA and the BMJ.  I am currently the lead statistician of two platform adaptive decentralised clinical trials to evaluate treatment for COVID-19 in the community.

I have currently the Deputy Director of the Primary Care Clinical Trials Unit (CTU) and lead a team of statisticians within the CTU.  I am a senior adviser for the NIHR Research and Design Services (South Central), panel member of the NIHR Research for Social Care funding programme and the Definitive Interventions and Feasibility Awards (HRB Ireland). I am also a member of the CHM Cancer Vaccines Expert Working Group (CVEWG).  I have sat on various NIHR funding boards and the Oxford Tropical Research Ethnics Committee. I am also a chair/member of data and safety monitoring committee, and the trial steering committee of several national and international trials.

My research interests include, platform trials, missing data, covariate adjustment in clinical trials, systematic review of reporting of clinical trials and prediction models.  

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