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Antiviral molnupiravir offers only modest longer-term benefits for COVID-19, finds new paper from the PANORAMIC trial

COVID-19 Clinical trials

Can the long-term consequences of COVID 19 be reduced through the use of novel antiviral medicines? New research from the PANORAMIC trial, run in NDPCHS Clinical Trial Unit and funded and delivered by the NIHR, has found that treating vaccinated, higher-risk adults with COVID-19 with the antiviral drug molnupiravir offers only modest benefits when it comes to reducing long term effects of the acute illness.

NDPCHS postgraduate programmes open for application for 2025

Students

We are now inviting applications for all of our postgraduate programmes based within the department for 2025.

Three top strategies for quitting smoking

Health behaviours

Top three strategies for quitting smoking: e-cigarettes, varenicline, and cytisine. New review summarises data from fourteen Cochrane Tobacco Addiction Reviews of over 150,000 participants, providing evidence-based guidance for smokers seeking to quit.

Celebrating the success of our 2024 UNIQ+ interns

The Nuffield Department of Primary Care Health Sciences congratulates its 2024 UNIQ+ interns for completing their summer research projects, contributing valuable insights in health care and gaining vital experience for their future careers.

PANORAMIC Trial Learnings: Shaping Future Pandemic Research

NIHR report highlights PANORAMIC trial's global impact on primary care pandemic research, offering key learnings and recommendations for future studies to enhance preparedness and patient outcomes.

The scale of Long COVID: New study highlights the widespread impact

COVID-19

A comprehensive state-of-the-art review published today in The Lancet has revealed the widespread impact of Long COVID, providing crucial insights into the condition's biological mechanisms and outlining key areas for future research.

Identifying early symptoms associated with a diagnosis of childhood, adolescent and young adult cancers

QResearch

Researchers from the Nuffield Department of Primary Care Health Sciences have conducted the largest ever study examining symptoms of cancer in children, teenagers and young adults (CTYA) presenting to GPs. The research, published in the British Journal of Cancer, provides crucial new insights that could help improve early diagnosis of cancer in young people.

Potential in deprescribing: reducing blood pressure drugs shows promise for improving older patients' care

In the largest study of its kind to date, new research from the Nuffield Department of Primary Care Health Sciences, University of Oxford has found that reducing blood pressure medication in older adults with well-controlled blood pressure is likely to be safe in the long term, allowing doctors to simplify medication regimes.

Congratulations to Hackathon Prize winners: Highlights from Centre for Digital Transformation of Health workshop

Congratulations to our students who participated in the Hackathon Prize competition as part of a workshop for the Centre for Digital Transformation of Health. DPhil student Gina Wren's team came in first-place and MSc in Applied Digital Health student Anton Elepaño's team took second-place.

Exciting Opportunity: MEdIC's Medical Education Masterclass Series 2024

Students Teaching

Medical Education Masterclass Series 2024: Open for Registration! Imperial College London's Medical Education Innovation and Research Centre (MEdIC) is offering its annual medical education masterclass series.

Junaid Hameed and Clare Hornby win Best Student Presentation Award at the British Journal of General Practice (BJGP) Research and Publishing Conference

Congratulations to students Junaid Hameed and Clare Hornby on their Best Student Presentation Award! Junaid and Clare are final-year medical students (now about to graduate) in the Nuffield Department of Primary Care Health Sciences. They were taking part in a project supervised by Dr Sharon Dixon. Read Junaid and Clare's reflections on their experience attending the conference and receiving the award below.

OpenSAFELY provides vital real-time data to support NHS ambition for safer opioid use

Big data

Amid concerns that the COVID-19 pandemic might have led to increases in opioid prescribing, a new study from researchers at the Bennett Institute for Applied Data Science, University of Oxford, demonstrates how the OpenSAFELY database can be used to conduct detailed analyses of opioid prescribing practices, in line with key recommendations from recent NHS England guidance aimed at preventing and reducing opioid harm.

Department's Centre for Research Equity launches historic partnership to advance health equity in Northern Ireland

Department's Centre for Research Equity partners with Northern Ireland to advance health equity. This groundbreaking collaboration aims to improve health outcomes, reduce disparities, and ensure research benefits all communities through inclusive, community-driven approaches.

A toast to Primary Care: Celebrating growth and Professor Richard Hobbs' leadership at NDPCHS summer party

Awards & appointments Internal

On Friday 21 June, more than 200 members of our department gathered for our summer party, held this year in honour of Professor Richard Hobbs, our outgoing Head of Department. The party was a perfect blend of celebration and reflection, marking the end of Richard’s 13-year tenure at the helm.

Study shows disparity in COVID-19 vaccines uptake for immunocompromised individuals, despite evidence of vaccine effectiveness and safety

COVID-19 QResearch

A new study by researchers at NDPCHS has shown disparities in vaccine uptake in immunocompromised individuals across ethnic and socioeconomic groups, despite evidence that vaccines are safe and effective for patients with weakened immune systems.

New sleeper frameworks to help better prepare for future pandemics

Researchers from NDPCHS and the Usher institute at the University of Edinburgh have developed a set of ‘sleeper frameworks’ – strategic plans designed for rapid deployment to significantly enhance disease surveillance and response capabilities – for use during future epidemics and pandemics.

PRINCIPLE and PANORAMIC teams honoured with prestigious Prix Galien Award

Awards & appointments COVID-19 Clinical trials

The teams behind the PRINCIPLE and PANORAMIC clinical trials, run in the Clinical Trials Unit at the Nuffield Department of Primary Care Health Sciences, have been awarded the prestigious Prix Galien Best Public Sector Innovation Award 2024 for their work in conducting innovative, large-scale clinical trials during the COVID-19 pandemic.

Comprehensive review confirms mask effectiveness against respiratory infections, urges better design and policy support

COVID-19 Infection, Respiratory and Acute Care Policy & health systems

New comprehensive review provides strong evidence that masks and respirators effectively reduce the transmission of respiratory infections like COVID-19, based on analysis of over 400 studies from multiple disciplines.

World hypertension day: How we’re tackling high blood pressure from pregnancy to later life

Cardiovascular & metabolic Digital health & innovation Public engagement & involvement

For World Hypertension Day 2024, discover three of our innovative studies – SNAP2, SHIP, and OPTIMISE 2 – aiming to improve blood pressure management across the life cycle through technology and patient involvement.

Ground-breaking art exhibition, The PANORAMIC PRINCIPLE, unveiled at Celebratory Symposium

Clinical trials

The PANORAMIC PRINCIPLE art exhibition, by CTU artist-in-residence Tanya Poole, was unveiled at the PRINCIPLE-PANORAMIC Celebratory Symposium this week. The portraits interpret the human experience of conducting and participating in the trials and honour the diverse array of participants, researchers, and medical professionals whose inclusive efforts set global benchmarks and transformed lives.

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