27 August 2021
Oxford researchers have today announced the results of a blood clot study, suggesting lower risk with vaccine than infection.
10 August 2021
Research into the risk of hospital admission from COVID-19 is recognised with a "Best Research Paper Award" from the journal Heart.
23 June 2021
From today, ivermectin is being investigated in the UK as part of the Platform Randomised Trial of Treatments in the Community for Epidemic and Pandemic Illnesses (PRINCIPLE), the world’s largest clinical trial of possible COVID-19 treatments for recovery at home and in other non-hospital settings.
12 April 2021
Inhaled budesonide, a common corticosteroid, is the world's first widely available, inexpensive drug found to shorten recovery times in COVID-19 patients aged over 50 who are treated at home and in other community settings, reports the PRINCIPLE trial in 1,779 participants. As of today, the treatment is available in UK primary care on a case-by-case basis.
Favipiravir to be investigated as a possible COVID-19 treatment for at-home recovery in the PRINCIPLE trial
8 April 2021
Could the antiviral favipiravir help transform COVID-19 into an illness that can be successfully treated by general practitioners?
19 March 2021
Close monitoring and evaluation as schools reopen crucial to inform ongoing policy
3 March 2021
From today, the UK’s national priority platform trial of Covid-19 treatments for recovery at home launches its investigation of the gout drug colchicine, and expands for the first time to include adults of any age.
Azithromycin and doxycycline are not generally effective against COVID-19 in patients treated at home, shows PRINCIPLE trial
25 January 2021
Update from the Chief Investigators of the Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE), 25 January 2021
Inhaled corticosteroids to be investigated as a possible treatment for Covid-19 in national PRINCIPLE Trial
27 November 2020
In Covid-19, inhaled budesonide may prevent damaging inflammation, stop the virus from getting into lung cells and inhibit viral replication.
3 November 2020
Led by a research team in the Nuffield Department of Primary Care Health Sciences, the University of Oxford will take part in a new pilot scheme to assess the use of Lateral Flow Tests (LFTs), a new COVID-19 test designed to identify asymptomatic individuals with the virus.
23 October 2020
The importance of patient and public contributors is recognised as key to the success of the study.
Britain’s most influential Hindu temple spreads awareness of the PRINCIPLE trial among Indian community
21 October 2020
Europe’s BAPS Swaminarayan Sanstha, the largest Hindu temple outside of India, is supporting their community during the coronavirus pandemic by spreading awareness of the PRINCIPLE trial of Covid-19 treatments.
21 October 2020
A new risk model, developed by UK researchers to predict a person’s risk of being admitted to hospital and dying from Covid-19 has been published by The BMJ
1 October 2020
More than 1000 people across the UK have signed-up to take part in the UK-wide PRINCIPLE Trial of potential community-based treatments for COVID-19, led by Oxford University.
7 July 2020
There is no evidence to suggest a daily combination of probiotics reduces the need for antibiotics to treat acute infections in care home residents, finds a study led by Oxford University researchers published in JAMA.