Simon de Lusignan

Professor of Primary Care and Clinical Informatics

I am a senior academic GP with research interests in clinical informatics and health outcomes.

My research interests focus on the use of routine data for surveillance, quality improvement, research and education as well as how technology has enabled new roles in health care and greater self-management.

I am Director of the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC). This is one of Europe's oldest sentinel systems. RCGP RSC has produced a weekly report of influenza, respiratory and other infections in primary care for over 50 years. RCGP RSC works closely with Public Health England (PHE) to report vaccine effectiveness. More information at: www.rcgp.org.uk/rsc

We have developed a digital hub - ORCHID - to support research platforms in addition to the RCGP RSC-Surveillance Platform. Details of how to collaborate with us to support clinical trials, or to access our data can be found at the Clinical Informatics and Health Outcomes research group website: ORCHID ::: Oxford-RCGP RSC | Clinical Informatics Research Group we are also included in the Health Data Research UK list of Trusted Research Environments.

Recent publications

Prevalence of depression and anxiety in people with inflammatory bowel disease and associated healthcare use: population-based cohort study.
Journal article

Irving P. et al, (2021), Evid Based Ment Health
Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial
Journal article

Butler CC. et al, (2021), The Lancet, 397, 1063 - 1074
Association Between Blood Pressure Control and Coronavirus Disease 2019 Outcomes in 45 418 Symptomatic Patients With Hypertension: An Observational Cohort Study
Journal article

Sheppard JP. et al, (2021), Hypertension (Dallas, Tex. : 1979), 77, 846 - 855
Adverse events of interest following influenza vaccination, a comparison of cell culture-based with egg-based alternatives: English sentinel network annual report paper 2019/20
Journal article

de Lusignan S. et al, (2021), The Lancet Regional Health - Europe, 2, 100029 - 100029
The impact of social and physical distancing measures on COVID-19 activity in England: findings from a multi-tiered surveillance system
Journal article

Bernal JL. et al, (2021), Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 26

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