Colleges
Collaborators
-
Chris Butler
Professor of Primary Care
-
Gail Hayward
Professor of Primary Care
-
Sarah Tonkin-Crine
Professor of Health Psychology
Jienchi Dorward
BSc, MBChB, MRCGP, MSc, DPhil
Academic Clinical Lecturer
I am an NIHR Academic Clinical Lecturer in the Nuffield Department of Primary Care Health Sciences at the University of Oxford. My research is based in South Africa and the UK, and focussed on management of infectious diseases in primary care. In Oxford I work in the Infections, Respiratory and Acute Care team and the NIHR HealthTech Research Centre in Community Healthcare. I am also an Honorary Associate Scientist at the Centre for the AIDS Programme of Research in South Africa (CAPRISA).
At CAPRISA, I primarily work on the SHAPE study; a collaboration with South African primary care services which uses de-identified routine data to evaluate the HIV/TB programme. I have been co-PI or co-Investigator on several randomised controlled trials of point-of-care HIV viral load and point-of-care urine tenofovir adherence tests, including the POwER and PHILA studies, and the US NIH funded STREAM and STREAM-HIV trials.
I have been heavily involved in COVID-19 research. I was a co-investigator and trial management group member for the PANORAMIC and PRINCIPLE trials, the UK national platform adaptive trials of antivirals and repurposed medications to treat COVID-19 in the community.
I previously worked at CAPRISA as a Research Clinician and Project Manager. I completed UK General Practice (Family Medicine) specialty training through clinical placements in the London Deanery, UK and Bethesda Hospital, South Africa, before doing the MSc in Public Health in Developing Countries at the London School of Hygiene & Tropical Medicine, and then a DPhil in Primary Care at the University of Oxford.
My work has been supported by funding from Wellcome, the Bill & Melinda Gates Foundation, the UK Global Challenges Research Fund and the National Institute of Health and Social Care Research (NIHR).
I am keen to discuss potential DPhil/PhD projects around primary care, HIV and global health.
Key publications
Urine tenofovir and dried blood spot tenofovir diphosphate concentrations and viraemia in people taking efavirenz and dolutegravir-based antiretroviral therapy
Journal article
Dorward J. et al, (2024), AIDS, 38, 697 - 702
Clinical outcomes with second-line dolutegravir in people with virological failure on first-line non-nucleoside reverse transcriptase inhibitor-based regimens in South Africa: a retrospective cohort study
Journal article
Asare K. et al, (2024), The Lancet Global Health, 12, e282 - e291
Diagnostic accuracy of a point-of-care urine tenofovir assay, and associations with HIV viraemia and drug resistance among people receiving dolutegravir and efavirenz-based antiretroviral therapy
Journal article
Dorward J. et al, (2023), Journal of the International AIDS Society, 26
Clinical outcomes after extended 12-month antiretroviral therapy prescriptions in a community-based differentiated HIV service delivery programme in South Africa: a retrospective cohort study
Journal article
Lewis L. et al, (2023), Journal of the International AIDS Society, 26
Implementation and outcomes of dolutegravir-based first-line antiretroviral therapy for people with HIV in South Africa: a retrospective cohort study
Journal article
Dorward J. et al, (2023), The Lancet HIV, 10, e284 - e294
Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial
Journal article
Yu LM. et al, (2021), Lancet, 398, 843 - 855
The impact of the COVID-19 lockdown on HIV care in 65 South African primary care clinics: an interrupted time series analysis
Journal article
Dorward J. et al, (2021), The Lancet HIV, 8, e158 - e165
Dolutegravir for first-line antiretroviral therapy in low-income and middle-income countries: uncertainties and opportunities for implementation and research
Journal article
Dorward J. et al, (2018), Lancet HIV, 5, e400 - e404
Recent publications
Point-of-care HIV viral load testing in a community antiretroviral therapy delivery programme: A randomised controlled trial (PHILA).
Journal article
Dorward J. et al, (2026), PLOS Glob Public Health, 6
Uptake and 24-month Outcomes of Dolutegravir- Versus Lopinavir-based Second-line Antiretroviral Therapy for People With HIV in South Africa: A Retrospective Cohort Study and Emulated Target Trial
Journal article
Brown JA. et al, (2025), Open Forum Infectious Diseases, 12
The PRINCIPLE randomised controlled open label platform trial of hydroxychloroquine for treating COVID19 in community based patients at high risk
Journal article
Hobbs FDR. et al, (2025), Scientific Reports, 15
Cost and clinical flow of point-of-care urine tenofovir testing for treatment monitoring among people living with HIV initiating ART in South Africa
Journal article
Wang M. et al, (2025), Journal of the International AIDS Society, 28
Viroimmunologic Model to Characterize the Antiviral Effect of Molnupiravir in Outpatients Infected With SARS-CoV-2: Implication for Treatment Duration
Journal article
Nguyen BT. et al, (2025), Journal of Infectious Diseases, 231, e1080 - e1090