Colleges
Contact information
simon.delusignan@phc.ox.ac.uk
simon.delusignanpa@phc.ox.ac.uk
01865 617 283
(ext. 17 283)
01865 289 344
(ext. 89 344)
Zahn Gowar
simon.delusignanpa@phc.ox.ac.uk
Research groups
Simon de Lusignan
Professor of Primary Care and Clinical Informatics
I am a senior academic GP with research interests in clinical informatics and health outcomes and lead the Clinical Informatics and Health Outcomes research group.. Alongside my Departmental role I am a Senior Research Fellow of Green Templeton College.
My research interests focus on the use of routine data for surveillance, quality improvement, research and education as well as how technology has enabled new roles in health care and support self-management. My principal areas of work are in monitoring acute respiratory infections and other diseases from routine health data and determining vaccine effectiveness. I also have a strong interest in cardiometabolic disease.
I am Director of the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC). This is one of Europe's oldest sentinel systems. The RSC has produced a weekly report of influenza, respiratory and other infections in primary care for nearly 60 years. The RSC is sponsored by, and works closely with the UK Health Security Agency (UKHSA) to to provide the national primary care sentinel network. More information at: www.rcgp.org.uk/rsc
The RSC now has over 2,000 general practice members sharing pseudonymised data, a registered population base of >23 million. We have direct links with our RSC member practices who collect samples and are also very willing to recruit to research studies.
Recent publications
ssessing the association between COVID-19 vaccination and thrombotic thrombocytopenia syndrome (ATTEST Study): Analyses of English data, 2020-2022
Journal article
Ordóñez-Mena JM. et al, (2026), International Journal of Infectious Diseases, 164
Differentiating the COVID-19 Infection and Vaccine Experiences of Patients With Systemic, Single Organ, and Overlap Immune-Mediated Inflammatory Disease: Protocol for a Secondary Analysis for Enhancing COVID-19 Vaccine Pharmacovigilance.
Journal article
Leston M. et al, (2026), JMIR Res Protoc, 15
The Third Study of Infectious Intestinal Disease (IID3 Study) in the Community: Protocol for UK-Based Prospective Cohort Studies Investigating the Disease Burden.
Journal article
Rowland BW. et al, (2026), JMIR Res Protoc, 15
Epidemiology of virologically confirmed RSV, influenza and COVID-19 in adults in England, 2023-2024: Primary Care Observational Study of Acute Respiratory Infection (ObservatARI).
Journal article
Ordóñez-Mena JM. et al, (2026), J Infect
Disparities in uptake of Shingrix® vaccine in immunosuppressed individuals in England: a population-based cohort study
Journal article
Barry EVH. et al, (2026), Vaccine, 72