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Gestational Diabetes Mellitus (diabetes in pregnancy, GDM) is known to be associated with an increased risk of adverse outcomes for a mother and her infant during pregnancy and birth, including pre-eclampsia, a greater risk of assisted delivery, and stillbirth.

A programme of research was undertaken to design the feasibility of a randomised clinical trial to compare the cost-effectiveness of permissive versus intensive intrapartum glycaemic control in pregnancies complicated by diabetes.

A mixed-methods study (GILD) was developed across seven work packages. The health economics aimed to provide early evidence on the economic aspects of glycaemic control in labour and an assessment of how to estimate and express cost-effectiveness.