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Glycaemic control in labour with Diabetes: a scoping study (GILD)

Gestational Diabetes Mellitus (diabetes in pregnancy, GDM) is known to be associated with an increased risk of adverse outcomes for a mother and her infant during pregnancy and birth, including pre-eclampsia, a greater risk of assisted delivery, and stillbirth.

A programme of research was undertaken to design the feasibility of a randomised clinical trial to compare the cost-effectiveness of permissive versus intensive intrapartum glycaemic control in pregnancies complicated by diabetes.

A mixed-methods study (GILD) was developed across seven work packages. The health economics aimed to provide early evidence on the economic aspects of glycaemic control in labour and an assessment of how to estimate and express cost-effectiveness.

Oxford project lead:

Collaborators:

Nia Wyn Jones, University of Nottingham
Eleanor Mitchell, University of Nottingham
Kate Walker, University of Nottingham
Susan Ayers, City University of London
Lucy Bradshaw, University of Nottingham
Georgina Constantinou, City University of London
Tasso Gazis, Nottingham University Hospitals NHS Trust
Shalini Ojha, University of Nottingham
Phoebe Pallotti, University of Nottingham
Rachel Plachcinski, Independent parent and public involvement consultant
Michael Rimmer, University of Edinburgh
Jim Thornton, University of Nottingham
Natalie Wakefield, University of Nottingham

Dates:

December 2020 – December 2022

Funder:

National Institute for Health Research (Health Technology Assessment Programme)