Our mission is to develop, deliver, interpret and disseminate patient-facing primary care research to the highest international standards.
The Primary Care Clinical Trials Unit is an integral part of the University of Oxford's Nuffield Department of Primary Care Health Sciences. Our research themes are aligned with the departmental priorities on infectious diseases, cardiovascular and metabolic disease, behavioural medicine and other topics of major national and international importance. In 2016 the unit recruited almost 6000 participants from around 600 sites in over 20 countries.
Collaborate with us
We welcome requests to collaborate on research and support studies.
Software
We develop our own bespoke clinical trial software, which is available for licensing.
Trials portfolio
Our extensive study portfolio provides benefits to patient health and well-being.
Our expertise
Our multidisciplinary team deliver all aspects of primary care clinical research studies.
Highlight publications
Effect of Probiotic Use on Antibiotic Administration among Care Home Residents: A Randomized Clinical Trial
Butler CC. et al, (2020), JAMA - Journal of the American Medical Association, 324, 47 - 56
C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations
Butler CC. et al, (2019), New England Journal of Medicine, 381, 111 - 120
Prevalence of chronic kidney disease in the community using data from OxRen: A UK population-based cohort study
Hirst JA. et al, (2020), British Journal of General Practice, 70, E285 - E293
TELEMONITORING AND/OR SELF-MONITORING OF BLOOD PRESSURE IN HYPERTENSION (TASMINH4): A RANDOMISED CONTROLLED TRIAL
McManus R. et al, (2018), JOURNAL OF HYPERTENSION, 36, E5 - E5
The unit is led by:
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Chris Butler
Professor of Primary Care
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Ly-Mee Yu
Associate Professor and Deputy Director Academic (Primary Care Clinical Trials Unit)
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Emma Ogburn
CTU Director of Operations
