World-leading Centre for Primary Care Research
Our Primary Health Care Clinical Trials Unit is a world-leading centre for primary care research, conducting high-quality clinical trials to improve patient and community health. The unit focuses on key research areas such as infectious diseases, cardiovascular health, and behavioural medicine. With a multidisciplinary team and strong partnerships, including the PCVC-CTU consortium and UK Clinical Research Network, the unit is committed to patient-centred care, rigorous research, and impactful dissemination of findings to influence health policies and practices.
CTU Leadership:
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Chris Butler
Professor of Primary Care
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Ly-Mee Yu
Professor of Clinical Trials and Biostatistics
Recruiting Trials
Learn about our recruiting trials
Collaborate with us
We welcome requests to collaborate on research and support studies.
Past Trials
Our extensive study portfolio provides benefits to patient health and well-being.
Clinical Trial Management Crash Course
Master the essentials of clinical trial management in this comprehensive three-day intensive course.
Latest news
Highlight publications
Effect of Probiotic Use on Antibiotic Administration among Care Home Residents: A Randomized Clinical Trial
Butler CC. et al, (2020), JAMA - Journal of the American Medical Association, 324, 47 - 56
C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations
Butler CC. et al, (2019), New England Journal of Medicine, 381, 111 - 120
Prevalence of chronic kidney disease in the community using data from OxRen: A UK population-based cohort study
Hirst JA. et al, (2020), British Journal of General Practice, 70, E285 - E293
TELEMONITORING AND/OR SELF-MONITORING OF BLOOD PRESSURE IN HYPERTENSION (TASMINH4): A RANDOMISED CONTROLLED TRIAL
McManus R. et al, (2018), JOURNAL OF HYPERTENSION, 36, E5 - E5