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World-leading Centre for Primary Care Research

Our Primary Care Clinical Trials Unit is a world-leading centre for primary care research, conducting high-quality clinical trials to improve patient and community health. We are a UKCRC registered clinical trials unit (Oxford Primary Care & Vaccines Collaborative CTU).

The unit focuses on key research areas such as infectious diseases, cardiovascular health, and behavioural medicine. We offer dynamic clinical trial design including platform trials, adaptive designs and innovation around complex interventions.

With a multidisciplinary team and strong partnerships nationally and internationally, the unit is committed to patient-centred care, rigorous research, and impactful dissemination of findings to influence health policies and practices. 

CTU Leadership:

A scientist in a lab coat smiles while writing notes, seated next to a microscope in a laboratory. Shelves filled with lab equipment and a computer screen are visible in the background.

recruiting trials

Learn about our recruiting trials                                                                                                                                                                                                                                              

Explore here
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collaborate with us

We welcome requests to collaborate on research and support studies.                                                                                                                                                   

Find out more
A chalkboard with the words 'Clinical Trial' written on it, placed on a turquoise wooden surface. Beside it are two blister packs of blue capsules and a stethoscope, symbolising medical research and clinical studies

Past Trials

Our extensive study portfolio provides benefits to patient health and well-being.                                                                                                                                                                            

Explore our research
A woman stands at the front of a desk in an office setting, engaging with three colleagues seated at the table. They are using computers and laptops, suggesting a collaborative meeting or discussion. The room has large windows allowing natural light and a view of greenery outside

Clinical Trial Management Crash Course

Master the essentials of clinical trial management in this comprehensive three-day intensive course.

More info

Highlight publications

Effect of Probiotic Use on Antibiotic Administration among Care Home Residents: A Randomized Clinical Trial

Butler CC. et al, (2020), JAMA - Journal of the American Medical Association, 324, 47 - 56

C-reactive protein testing to guide antibiotic prescribing for COPD exacerbations

Butler CC. et al, (2019), New England Journal of Medicine, 381, 111 - 120

Prevalence of chronic kidney disease in the community using data from OxRen: A UK population-based cohort study

Hirst JA. et al, (2020), British Journal of General Practice, 70, E285 - E293

TELEMONITORING AND/OR SELF-MONITORING OF BLOOD PRESSURE IN HYPERTENSION (TASMINH4): A RANDOMISED CONTROLLED TRIAL

McManus R. et al, (2018), JOURNAL OF HYPERTENSION, 36, E5 - E5