Clinical Informatics and Health Outcomes Research Group (CIHORG)
- 01865 289344
 - simon.delusignanpa@phc.ox.ac.uk
 
Data from over 2000 general practices
Produces weekly reports on communicable and respiratory diseases
The Clinical Informatics and Health Outcomes Research Group (CIHORG) is the home of the Oxford-Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC), one of the world's oldest sentinel networks, as well as involved in a wide range of observational and interventional research.
The RSC has been involved in the sentinel surveillance of respiratory disease, including influenza and COVID-19, for over 50 years. It is a long standing collaboration between the RCGP and the UK Health Security Agency (UKHSA). The scale of the RSC and it capabilities have expanded considerably since 2013, and described in the RSC’s 2023-2024 protocol and recent cohort profile. The lessons from the COVID-19 pandemic included the importance of our network recording high quality data, linking primary care data to virology and other data sources, and providing rapid data access, if we are to be ready for the next.
The RSC collected pseudonymised data from over 2,000 general practice network members and is used for disease surveillance and research. CIHORG has direct links to the RSC member practices who record high quality data, collect virology, serology and other samples, and recruit practices into research projects.
CIHORG is led by: Simon de Lusignan – Professor of Primary Care & Clinical Informatics, who can be contacted via Zahn Gowar. Our chief statistician is Mark Joy.
CIHORG is organised into two theme groups:
Surveillance and infectious disease epidemiology, led by Uy Hoang, with project management provided by Karina O’Neill and Dominic Dunn (laboratory links).
Cardiometabolic research is lead by Jose Ordonez-Mena, with project management provided by Filipa Ferreira.
Current Projects
Current projects in addition to disease surveillance include:
- ObservatARI study of intensive surveillance of acute respiratory infections (ARI) in primary care with a focus on respiratory syncytial virus (RSV)
 - The Third study of Intestinal Infectious Disease (IID3). Food Standards agency sponsored study of IID across the UK.
 - Bristol Medicine Review Toolkit Study (BRISMED)
 - SAFER
 - SHADE (GSK grant)
 - MONITORY - Audit-based education to implement NICE Do-Not-Do recommendations in people with cardiometabolic multimorbidity
 - COMBI KID
 - FluSNIFF
 - HEALD
 - STANDOUT
 
Contact us
Gibson Building, Radcliffe Observatory, Woodstock Rd, Oxford OX2 6GG
email: simon.delusignanpa@phc.ox.ac.uk
Our Team
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Simon de Lusignan
Professor of Primary Care and Clinical Informatics
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Gavin Jamie
Clinical Phenotype Group Lead
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Uy Hoang
Research Fellow
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José M. Ordóñez-Mena
Senior Medical Statistician
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Filipa Ferreira
Senior Project Manager
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Karina O'Neill
Senior Project Manager
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Fatima Batool
Senior Researcher
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William Hinton
Research Fellow
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Xinchun Gu
Researcher
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Bernardo Meza-Torres
Researcher
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Elizabeth Button
Practice Liaison Team Lead
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Jack Macartney
Practice Liaison Officer / Research Facilitator
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Timea Suli
Practice Liaison Officer | Research Facilitator
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Jessica Smylie
Practice Liaison Officer / Research Facilitator
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Ellya Enesca
Research Facilitator / Practice Liaison Officer
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Xuejuan Fan
SQL Developer/Data Scientist
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Rachel Byford
Lead Data Architect
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Mili Muraleedharan
Operations Manager, Data team
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Gunjan Jiwnani
SQL Developer
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Cecilia Okusi
Data Scientist and DPhil Candidate
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                                Mark Joy
Senior Statistician
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                                Sneha Anand
Project Manager
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                                William Elson
Doctoral Clinical Research Fellow
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                                Rosalind Goudie
Senior SQL Developer
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Zahn Gowar
Executive Assistant to Prof Simon de Lusignan
 
Trials and Prospective Studies
Current and previous studies
Weekly communicable and respiratory disease report
(via RCGP)
Surveillance
Research and surveillance centre
RCGP RSC virology practices dashboard
RCGP RSC virology practices sampling and detection of influenza and other monitored viruses.
Latest publications
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                Hepatitis A vaccination coverage in adults with chronic liver disease in primary care in England: a retrospective cohort study
            
            
                
Journal article
Meza-Torres B. et al, (2025), Lancet Public Health, 10, e647 - e655
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                The Impact of Point-of-Care Testing for Influenza on Antimicrobial Stewardship in UK Primary Care: Nested Cohort Study
            
            
                
Journal article
Hoang U. et al, (2025), Jmir Public Health and Surveillance, 11
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                Clarity of healthcare roles in electronic health records.
            
            
                
Journal article
Tzortziou Brown V. et al, (2025), Br J Gen Pract
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                Effectiveness of non-pharmaceutical interventions as implemented in the UK during the COVID-19 pandemic: a rapid review
            
            
                
Journal article
Ashcroft T. et al, (2025), Journal of Public Health, 47, 268 - 302
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                Economic impact of RSV infections in young children attending primary care: a prospective cohort study in five European countries, 2021 to 2023
            
            
                
Journal article
Sankatsing VDV. et al, (2025), Eurosurveillance, 30
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                Disparities in the care and direct-acting oral anticoagulant (DOAC) management in atrial fibrillation (AF) and chronic kidney disease (CKD) in English primary care between 2018 and 2022: Primary care sentinel network database study
            
            
                
Journal article
Emanuel S. et al, (2025), Open Heart, 12
 
Latest News
Key blood test for identifying people with heart failure less accurate in those with atrial fibrillation, new study finds
30 October 2025
A large new study led by researchers in the Nuffield Department of Primary Care Health Sciences has found that a common blood test used to help diagnose heart failure is less accurate in people who also have atrial fibrillation (AF).
Soft drinks tax changes 'miss opportunity' to tackle highest-sugar products, say Department researchers
28 October 2025
Department researchers find government's soft drinks tax changes miss opportunity to maximise health benefits. Analysis shows targeting highest-sugar products could remove twice as much sugar from market as current proposals, particularly benefiting deprived areas.
Oxford team wins two of three top RCGP Research Paper of the Year awards
17 October 2025
Department researchers win two of three Royal College of General Practitioners Research Paper of the Year Awards 2025, recognising groundbreaking work on hybrid general practice models and remote care training from the NIHR-funded Remote by Default 2 programme.