Clinical Informatics and Health Outcomes Research Group (CIHORG)
Clinical Informatics and Health Outcomes Research Group
The Clinical Informatics and Health Outcomes Research Group (CIHORG) is the home of the Oxford-Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC), one of the world's oldest sentinel networks and is also involved in observational and interventional research.
CIHORG manages the Oxford-RCGP RSC network of practices, to enable the sharing of high quality data, collect virology, serology and other samples, and recruit practices into research projects.
The group is led by: Simon de Lusignan – Professor of Primary Care & Clinical Informatics, and RSC Director, who can be contacted via Zahn Gowar. Our chief statistician is Mark Joy.
CIHORG is organised into two theme groups:
- Surveillance and infectious disease epidemiology, led by Uy Hoang, with project management provided by Karina O’Neill and Dominic Dunn (laboratory links).
- Cardiometabolic research is lead by Jose Ordonez-Mena, with project management provided by Filipa Ferreira.
Oxford-RCGP Research & Surveillance Centre
As one of Europe's oldest general practice sentinel networks, The Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) has been the primary source for disease surveillance in England since 1957.
The University of Oxford has hosted the Oxford-RCGP Research and Surveillance Centre since 2019, and is commissioned by the UK Health Security Agency (UKHSA) to provide surveillance services, in partnership with RCGP, across general practices in England.
The Oxford-RCGP RSC network has grown significantly since 2020, from approximately 500 to over 2,000 nationally representative general practices in England. The network enables aggregated health related data to be used for regular surveillance reporting to UKHSA (for approximately 40 monitored diseases). The Oxford-RCGP RSC also undertakes research on a project-by-project basis which can include practices in England and the devolved nations.
The scale of the RSC and it capabilities have expanded considerably since 2019, and described in the RSC’s 2023-2024 protocol and recent cohort profile. During the COVID-19 pandemic, we were able to demonstrate the importance of our network in recording high quality data, linking primary care data to virology and other data sources, and providing rapid data access, which would provide benefits for health service planning for future pandemics.
Current Projects
Current projects in addition to disease surveillance include:
- ObservatARI
- The Third study of Intestinal Infectious Disease (IID3)
- Bristol Medicine Review Toolkit Study (BRISMED)
- SAFER
- SHADE (GSK grant)
- COMBI KID
- FluSNIFF
- HEALD
- STANDOUT
Medical Director
Contact us
Gibson Building, Radcliffe Observatory, Woodstock Rd, Oxford OX2 6GG
01865 289344
email: simon.delusignanpa@phc.ox.ac.uk
Upcoming Events 2025
Upcoming Events 2026
Best Practice Conference
25th & 26th February
London
Our Team
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Simon de Lusignan
Professor of Primary Care and Clinical Informatics
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Gavin Jamie
Clinical Phenotype Group Lead
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Bernardo Meza-Torres
Researcher
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Elizabeth Button
Practice Liaison Team Lead
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Jack Macartney
Practice Liaison Officer / Research Facilitator
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Timea Suli
Practice Liaison Officer | Research Facilitator
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Jessica Smylie
Practice Liaison Officer / Research Facilitator
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Ellya Enesca
Research Facilitator / Practice Liaison Officer
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Xuejuan Fan
SQL Developer/Data Scientist
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Rachel Byford
Lead Data Architect
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Mili Muraleedharan
Operations Manager, Data team
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Gunjan Jiwnani
SQL Developer
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Uy Hoang
Research Fellow
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Cecilia Okusi
Data Scientist and DPhil Candidate
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Mark Joy
Senior Statistician
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Sneha Anand
Project Manager
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William Elson
Doctoral Clinical Research Fellow
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Rosalind Goudie
Senior SQL Developer
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Zahn Gowar
Executive Assistant to Prof Simon de Lusignan
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José M. Ordóñez-Mena
Senior Medical Statistician
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Filipa Ferreira
Senior Project Manager
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Karina O'Neill
Senior Project Manager
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Fatima Batool
Senior Researcher
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William Hinton
Research Fellow
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Xinchun Gu
Researcher
Trials and Prospective Studies
Current and previous studies
Weekly communicable and respiratory disease report
(via RCGP)
Latest publications
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Agreement and utility of coded primary and secondary care data for long-term follow-up of clinical trial outcomes
Journal article
Wang A. et al, (2025), BMC Medical Research Methodology, 25
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Correction to: Navigating the complexities of end-stage kidney disease (ESKD) from risk factors to outcome: insights from the UK Biobank cohort (BMC Nephrology, (2025), 26, 1, (168), 10.1186/s12882-025-04090-7)
Journal article
Kar D. et al, (2025), BMC Nephrology, 26
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Team climate, job satisfaction, burnout and practice performance: results of a national survey of staff in general practices in England
Journal article
Williams P. et al, (2025), BMC Primary Care, 26
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Navigating the complexities of end-stage kidney disease (ESKD) from risk factors to outcome: insights from the UK Biobank cohort
Journal article
Kar D. et al, (2025), BMC Nephrology, 26
Latest News
Maternal RSV vaccine prevents hundreds of infant hospitalisations in first real-world national study
4 December 2025
A major new study has shown that the risk of hospital admissions for young babies with serious respiratory infections reduced by more than 80% in Scotland following a new maternal vaccination programme against respiratory syncytial virus (RSV).
MSc in Applied Digital Health alumnus Dr James Leigh publishes dissertation in Clinical & Experimental Ophthalmology, advancing research on AI-enabled diabetic retinopathy screening
3 December 2025
MSc in Applied Digital Health alumnus Dr James Leigh, now a DPhil candidate in Translational Health Sciences, has published his MSc dissertation in Clinical & Experimental Ophthalmology, offering important evidence on the cost-effectiveness of AI-enabled diabetic retinopathy screening at a time when health systems worldwide are evaluating the role of AI in frontline care.
Dr Joanna Crocker appointed Chief Scientific Advisor to help tackle health inequalities in Oxfordshire
28 November 2025
Senior Researcher Dr Joanna Crocker appointed Chief Scientific Advisor to lead community-engaged research tackling health inequalities in Oxfordshire.
