Clinical Informatics and Health Outcomes Research Group (CIHORG)
- digital-data-ai
- infection-respiratory
Clinical Informatics and Health Outcomes Research Group
The Clinical Informatics and Health Outcomes Research Group (CIHORG) is the home of the Oxford-Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC), one of the world's oldest sentinel networks and is also involved in observational and interventional research.
CIHORG manages the Oxford-RCGP RSC network of practices, to enable the sharing of high quality data, collect virology, serology and other samples, and recruit practices into research projects.
The group is led by: Simon de Lusignan – Professor of Primary Care & Clinical Informatics, and RSC Director, who can be contacted via Zahn Gowar. The CIHORG is composed of researcher fellows, statisticians, data curators, SQL developers, practice liaison officers and project managers. The teams research interests are in clinical informatics, which include disease surveillance, quality improvement (QI), measuring health outcomes from routine data, incorporating technology into clinical workflow, and new technology enabled roles in health care. Developing more robust methods of collecting and harnessing real world evidence (RWE).
CIHORG is organised into two theme groups:
- Surveillance and infectious disease epidemiology, led by Uy Hoang, with project management provided by Sneha Anand and Dominic Dunn (laboratory links).
- Cardiometabolic research is lead by Jose Ordonez-Mena, with project management provided by Filipa Ferreira.
Oxford-RCGP Research & Surveillance Centre
As one of Europe's oldest general practice sentinel networks, The Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) has been the primary source for disease surveillance in England since 1957.
The University of Oxford has hosted the Oxford-RCGP Research and Surveillance Centre since 2019, and is commissioned by the UK Health Security Agency (UKHSA) to provide surveillance services, in partnership with RCGP, across general practices in England.
The Oxford-RCGP RSC network has grown significantly since 2020, from approximately 500 to over 2,000 nationally representative general practices in England. The network enables aggregated health related data to be used for regular surveillance reporting to UKHSA (for approximately 40 monitored diseases). The Oxford-RCGP RSC also undertakes research on a project-by-project basis which can include practices in England and the devolved nations.
The scale of the RSC and it capabilities have expanded considerably since 2019, and described in the RSC’s 2023-2024 protocol and recent cohort profile. During the COVID-19 pandemic, we were able to demonstrate the importance of our network in recording high quality data, linking primary care data to virology and other data sources, and providing rapid data access, which would provide benefits for health service planning for future pandemics.
Current Projects
Current projects in addition to disease surveillance include:
- ObservatARI
- The Third study of Intestinal Infectious Disease (IID3)
- Bristol Medicine Review Toolkit Study (BRISMED)
- SAFER
- SHADE (GSK grant)
- COMBI KID
- FluSNIFF
- HEALD
- STANDOUT
- HealthIntelAct
Medical Director
Contact us
Gibson Building, Radcliffe Observatory, Woodstock Rd, Oxford OX2 6GG
01865 289344
email: simon.delusignanpa@phc.ox.ac.uk
Upcoming Events 2025
Upcoming Events 2026
Best Practice Conference
25th & 26th February
London
Our Team
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Simon de Lusignan
Professor of Primary Care and Clinical Informatics
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Gavin Jamie
Clinical Phenotype Group Lead
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Bernardo Meza-Torres
Researcher
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Elizabeth Button
Practice Liaison Team Lead
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Jack Macartney
Practice Liaison Officer / Research Facilitator
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Timea Suli
Practice Liaison Officer | Research Facilitator
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Jessica Smylie
Practice Liaison Team Lead
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Xuejuan Fan
SQL Developer/Data Scientist
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Rachel Byford
Lead Data Architect
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Mili Muraleedharan
Operations Manager, Data team
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Gunjan Jiwnani
SQL Developer
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Uy Hoang
Research Fellow
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Cecilia Okusi
Data Scientist and DPhil Candidate
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Mark Joy
Senior Statistician
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Sneha Anand
Project Manager
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William Elson
Clinical Researcher
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Rosalind Goudie
Senior SQL Developer
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Zahn Gowar
Executive Assistant to Prof Simon de Lusignan
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José M. Ordóñez-Mena
Senior Medical Statistician
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Filipa Ferreira
Senior Project Manager
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Karina O'Neill
Senior Project Manager
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Fatima Batool
Senior Researcher
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William Hinton
Research Fellow
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Xinchun Gu
Researcher
Trials and Prospective Studies
Current and previous studies
Weekly communicable and respiratory disease report
(via RCGP)
Latest publications
Nirmatrelvir-ritonavir versus usual care in at-risk adults with early SARS-CoV-2 infection in the UK, 2022-23: virological and immunological results of an open-label randomised trial (PANORAMIC).
Journal article
Lowe DM. et al, (2027), Lancet Microbe
Association between Great Salt Lake desiccation, air quality, and major depressive episodes: an ecological study.
Journal article
Neelam M. et al, (2027), Lancet Planet Health
Antibiotic prescribing and use in United Kingdom general practices in socio-economically deprived areas: a critical interpretive synthesis
Journal article
Bell A. et al, (2026), Journal of Health Equity, 3
Associations of Alzheimer’s disease with inpatient hospital costs and with quality-adjusted life years: evidence from conventional and Mendelian randomization analyses in the UK Biobank
Journal article
Dixon P. and Anderson E., (2026), Cost Effectiveness and Resource Allocation, 24
Latest News
MSc in Translational Health Sciences to AI Innovation in autism care: Dr Ali Yildirim showcases his work in Lean Canvas presentation with Oxford University Innovation
22 May 2026
Dr Ali Yildirim is a recent alumnus from the MSc in Translational Health Sciences programme. He shares how his learnings on the course played an important role in shaping his work with DeepSynaps on the platform Harmony, designed to support families and professionals working with children with autism. Ali recently showcased this work during his Lean Canvas presentation with Oxford University Innovation.
New study reveals compounding quality-of-life burden after miscarriage
20 May 2026
A new study reveals that the quality-of-life impact of miscarriage compounds with repeated losses, with a second miscarriage marking a key turning point for mental wellbeing. The findings contributed to Tommy's Graded Model of Miscarriage Care report, supporting calls for earlier, more personalised miscarriage care and support.
Major study highlights promise of digital technology in improving hypertension care across sub-Saharan Africa
13 May 2026
A major international study published today in BMJ Public Health has found that a digitally enabled healthcare programme was associated with significant improvements in blood pressure control among people living with hypertension across sub-Saharan Africa.
