Infections and Acute Care
We investigate infectious diseases in primary care to find out how we can identify patients with serious infection, and more effective ways of diagnosing and treating patients with common infections.
We are working on a number of studies looking at how to diagnose and treat various common infectious diseases in children and adults in primary care.
Our work is important because it will help primary care clinicians to decide how best to identify which patients presenting with common symptoms such as coughs and colds are most likely to develop serious complications. This will help GPs know which patients are most likely to benefit from antibiotics. This can help to reduce unnecessary prescribing of antibiotics that is adding to resistance to antibiotics in many countries. We are running a number of very large studies to help answer these questions, which involve recruiting thousands of patients from across the UK.
We are also examining novel ways of diagnosing other infections such as whooping cough in people presenting with cough, as this may be an important cause of persistent coughing even in children and adults who have been vaccinated against this infection. We are also examining how many children with a persistent cough may have whooping cough; and trialling a drug which may be an effective treatment for persistent coughs.
In parallel, we are running trials to investigate treatments other than antibiotics for patients presenting with common cough and cold symptoms. This may give GPs and patients treatment options other than antibiotics to help relieve symptoms for these common illnesses.
Many of our researchers are major contributors to the NIHR Diagnostic Evidence Co-operative Oxford which is hosted by this department. Our researchers also lead the Behaviour, Implementation Science and Qualitative methods in Infections research Team which utilises behavioural science and qualitative methods to identify how to deliver better primary care for patients with infections.
Our Team
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Oliver Van Hecke
Senior Clinical Research Fellow
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Chris Butler
Professor of Primary Care
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Gail Hayward
Associate Professor
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Clare Goyder
Wellcome Trust Doctoral Research Fellow
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Jienchi Dorward
Academic Clinical Lecturer
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Philip Turner
Manager and Senior Researcher, NIHR Community Healthcare MIC
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Abigail Moore
Wellcome Trust Doctoral Research Fellow
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Anthony Bell
Probationary Research Student
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Elizabeth Thomas
DPhil Candidate
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Fiona Mowbray
Qualitative Researcher
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Margaret Głogowska
Senior Researcher
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Joseph Lee
NIHR In Practice Fellow
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Runa Lazzarino
Qualitative Research Fellow
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Tori Ford
NIHR Doctoral Research Fellow
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Aleksandra (Ola) Borek
Senior Qualitative Researcher in Behavioural Science
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Kome Gbinigie
Post-doctoral researcher
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Sarah Tonkin-Crine
Associate Professor & Health Psychologist
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Marta Wanat
Senior Qualitative Researcher in Behavioural Science
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Marta Santillo
Qualitative Research Fellow
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Helen Ashdown
Clinical Research Fellow
Latest publications
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Coaxing Corporations: Enriching the conceptualization of Government as strategic actors
Journal article
GILL M. and Gill DJ., (2023), Strategic Management Journal
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Strategies for identifying patients for deprescribing of blood pressure medications in routine practice: An evidence review
Journal article
SHEPPARD J. and MCMANUS R., (2023), Hypertension
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The ethical challenges of diversifying genomic data: A qualitative evidence synthesis
Journal article
Hardcastle F. et al, (2023), Cambridge Prisms: Precision Medicine, 1 - 39
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Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network meta-analyses
Journal article
Lindson N. et al, (2023), The Cochrane database of systematic reviews, 9
Current Projects
ARCHIVE PROJECTS
Latest news
New antiviral, Paxlovid, added to PANORAMIC study
12 April 2022
Preventing long-term pain from shingles
30 March 2022