A open, collaborative, and multidisciplinary group working with clinicians, researchers, and patients to improve pathways to cancer diagnosis.
A major focus of the group is building interdisciplinary teams to deliver projects to improve cancer control in primary care with impact and direct patient benefit.
To do this the cancer research theme works closely with patients, primary care professionals, cancer charities, researchers from other disciplines and institutions, NHS commissioners, diagnostics services and companies, and cancer care in the hospital setting.
This multidisciplinary approach enables the team to use the most appropriate research methodologies to address pressing research questions that have arisen out of direct clinical care.
Our work is organised into four themes: health records data, clinical studies, implementation science, and diagnostic reasoning.
Cancer Sub Themes
Health Records Data
We aim to produce high impact research that makes a difference to public health and healthcare provision.
- BLOTTED: BLOod Test Trend for cancEr Detection an observational and prediction model development study using English primary care electronic health records data
- CANBACK: Cancer in people presenting with back pain in Primary Care : A prevalence and diagnostic accuracy study
- CASNET: CAncer Safety NETting
- CASNET2: A clinical trial to evaluate electronic safety netting for suspected cancer
- GLANCE: A mixed methods study investigating Gut feeLings for cANCEr in general practice
- LOWCAN: Loss Of Weight as predictor of CANcer in primary care
- MAINROUTE: Monitoring Attendance, INvestigation, Referral and OUTcomes in primary care: impact of and recovery from COVID-19 lockdown
- NETTD: Safety-NETting for Timely Diagnosis in primary care
- SCAN: the Suspected CANcer Diagnostic Pathway
- SympFIT: Symptomatic Faecal Immunochemical Testing: Understanding the diagnostic value of FIT in patients with symptoms of colorectal cancer
- SYMPLIFY: A Study to check the performance of a MULTI-CANCER EARLY DETECTION blood test that may help early identification of many different types of cancer
Immunisations and imagining imperilled fertility: Women's trials of COVID-19 vaccines and reproductive/citizenship transgressions in pandemic times
Qureshi K. et al, (2023), Women's Studies International Forum, 100
Predicting the risk of acute kidney injury in primary care: derivation and validation of STRATIFY-AKI
Koshiaris C. et al, (2023), The British journal of general practice : the journal of the Royal College of General Practitioners, 73, e605 - e614
Should we? Could we? Feasibility of interventions to support prevention or early diagnosis of future cancer following urgent referral: A qualitative study
Evans REC. et al, (2023), Patient Education and Counseling, 112
Bridging the Gap: Primary Care Clinical Trials Unit and Cancer theme join OCTO in CRUK Collaboration
In the UK today 1000 people will be diagnosed with cancer. The earlier a cancer is caught the more treatment options are available. A core strategy within the NHS Long Term Plan is to diagnose 75% of cancers at an early stage by 2028. Primary care plays an essential role in meeting this target with the majority of patients diagnosed with cancer first presenting to their GP with symptoms.
Claire Friedemann Smith, Brian Nicholson and Georgia Black reflect on their visit to the first in-person Society to Improve Diagnosis in Medicine (SIDM) conference since Covid-19 in Utrecht, the Netherlands.
The BLOTTED study has established a network of researchers at various career stages interested in blood test trend for cancer detection. Blood test trend might tell GPs more information than single blood test results. A small change from a steady trend could be more useful for identifying patients at risk of undiagnosed cancer than waiting for a blood test value to fall outside a fixed “normal” range.
When it comes to diagnosing and treating non-specific symptoms (NSS) in cancer patients, a holistic approach is essential. However, the implementation of non-specific symptom pathways and national policies promoting holistic care can vary greatly among healthcare providers. In our workshop presented at the Cancer in Primary Care conference at Worcester College, Oxford, we discussed key challenges and future directions for research in providing comprehensive care to those with NSS.