At number one, we have, 'Understanding the role of GPs’ gut feelings in diagnosing cancer in primary care: a systematic review and meta-analysis of existing evidence', exploring the origins of GPs’ gut feelings for cancer, their use, and their diagnostic utility. The study concluded that GPs' gut feelings can help predict cancer diagnosis.
This study was led by Oxford researchers, Claire Friedemann Smith, Sue Ziebland, Professor of Medical Sociology and Brian D Nicholson, Academic Clinical Lecturer and GP, and also included research fellow, Sarah Drew, at London School of Economics and Political Science.
'Prevalence of chronic kidney disease in the community using data from OxRen: a UK population-based cohort study', which identified that almost half of individuals aged >60 years with Chronic Kidney Disease, may be undiagnosed.
This study was led by the following Oxford researchers, many of whom are part of the NIHR Oxford Biomedical Research Centre: Jennifer A Hurst, Richard J McManus, Emma Ogburn, José M Ordóñez Mena, Brian Shine, Clare J Taylor, Maria DLA Vazquez-Montes, Yaling Yang and our head of department, Richard Hobbs.
'Contribution of paramedics in primary and urgent care: a systematic review', a study looking to identify the types of clinical roles paramedics are undertaking in primary and urgent care settings within the UK.
This study was led by Oxford researchers, Georgette Eaton, Clinical Doctoral Fellow, Geoff Wong, Clinical Research Fellow, Veronika Williams, Honorary Researcher at the Bodleian Library, Nia Roberts, Bodleian outreach librarian and information specialist and Kamal R. Mahtani, GP and Associate Professor.
'Trends and variation in unsafe prescribing of methotrexate: a cohort study in English NHS primary care', with the aim of describing trends in GP prescribing of methotrexate over time; the harm associated with methotrexate errors at a national level; ascertaining variation between practices and clinical commissioning groups (CCGs) in their implementation of the safety guidance; and mapping current variations at CCG and practice level. The study determined that to avoid overdose, GPs should only prescribe 2.5mg tablets.
All authors are part of the departments' EBM datalab. Full team: Briana MacKenna, Honorary Research Fellow, Helen J Curtis, Alex J Walker, Richard Croker, all researchers, Seb Bacon, Chief Technology Officer and Ben Goldacre, Director.
'Oseltamivir for coronavirus illness: post-hoc exploratory analysis of an open-label, pragmatic, randomised controlled trial in European primary care from 2016 to 2018', a study designed to determine whether adding oseltamivir to usual care reduces time to recovery in symptomatic patients who have tested positive for coronavirus (not including SARS-CoV-2). The study found that patients testing positive for coronavirus recovered sooner with oseltamivir.
Oxford authors are Christopher Butler, Professor or Primary Care, Emily Bongard, Senior Clinical Trial Manager and Nina Gobat, Senior Researcher.